One of the guests on Mr. King’s program was a well-respected integrative pediatrician by the name of Dr. Jay Gordon. He pointed out a particularly salient point that I think is worth repeating. According to Dr. Gordon, the biggest danger of the H1N1 virus “is a secondary bacterial infection almost all the time. This virus is not virulent. It’s not powerful enough to actually kill very many people, if any. But the immune system is set up to get a secondary bacterial infection. If that’s not taken care of, you can have a fatal case.” (1)

Now, a team of researchers from the University of Alabama at Birmingham, believe they’ve found a natural way to assist the body in battling the H1N1 flu. It appears that the answer may lie in healthy foods and, perhaps, nutritional supplements. The “new” discovery centers around the effects of the H1N1 virus on lung tissue. A specific protein produced by this viral offender, known as the “M2 protein”, seems to damage pulmonary cells and prevents the lungs from effectively removing liquids which can lead to pneumonia and related complications. The take home message from the authors of the study is not that antioxidants will replace vaccines or other conventional treatments, but rather that they may play an invaluable role in dealing with influenza once it has already taken hold. (2)

There’s no question that these new findings are welcome news. But as it turns out, only the “M2 protein” aspect of this research is actually novel. Studies and even summary articles pertaining to the connection between antioxidants and influenza can be found in the scientific literature dating back at least 13 years. The trouble is, such research generally doesn’t get much play. That’s likely to change because of the Alabama data and the current concern about this flu pandemic. (3,4,5)

There are several antioxidants in particular that are documented as possessing activity against the influenza virus. Before I mention them, I want to point out that many naturopathic flu remedies are known sources of potent antioxidants. In the past I’ve mentioned a variety of botanical extracts (echinacea, elderberry, ginseng, green tea, Umcka, etc.) that are clinically validated with regard to immune stimulating and anti-viral properties. Every one of these is also a rich source of antioxidants. Is this simply a coincidence? Unlikely. (6,7,8,9,10)

• N-Acetyl Cysteine (NAC) - A laboratory study from September 2009 determined that NAC can inhibit the replication of the influenza virus and may promote an anti-inflammatory effect in lung cells. The German researchers helming the trial commented that, “antioxidants like NAC represent a potential additional treatment option that could be considered in the case of an influenza A virus pandemic”. This most recent study adds to a prior experiment from 2002 that established NAC’s immune boosting properties in vitro. In addition, a study from over a decade ago proved the worth of NAC in a human model. 262 men and women suffering from “influenza-like symptomatology” received either a placebo or NAC (600 mg) twice daily for 6 months. According to the authors of the trial, “NAC treatment was well tolerated and resulted in a significant decrease in frequency of influenza-like episodes, severity and length of time confined to bed”. They go on to remark that NAC did not prevent the flu but did “reduce the incidence of clinically apparent disease” and that it may be most useful in high risk populations. (11,12,13)
• Resveratrol - This “red wine” antioxidant has been the subject of numerous preliminary experiments involving viruses. A group of Italian scientists recently concluded that the “antiviral properties of resveratrol make it a potential candidate for the clinical control of proliferative (cancer) as well as viral pathologies”. A 2006 study in the journal Inflammopharmacology mentions that resveratrol (RSV) possesses “inhibitory effects on influenza virus replication”. Furthermore, an animal based experiment from 2008 examined the effects of resveratrol in rats exposed to pneumonia. It was determined that pretreatment with RSV “decreased bacterial burden in the infected lungs”, improved immune function (via Natural Killer cell activity) and ultimately reduced the mortality rate. A decline in lung inflammation was also noted in the animals treated with resveratrol. (14,15,16)
• Selenium - A lack of the trace mineral selenium has been implicated in compromised immune function. In fact, a flat out deficiency appears to affect the way we humans react to exposure to influenza, particularly in the epithelial cells located in the lungs. In addition, a 2004 study in 66 seniors found that a nutritional supplement containing selenium enhanced immune performance and resulted in fewer sick days due to upper respiratory infections. The duration of the trial was approximately 6 months and was placebo-controlled. All of the participants were also given standard flu vaccinations. (17,18,19)

• Vitamin C - There is a little known but clinically-proven strategy for protecting against “virus-induced respiratory infections”. This is according to a trial from 1999. The protocol involves taking high doses of vitamin C at the onset of “cold and flu symptoms”. Specifically, 252 test subjects took “hourly dosages of 1,000 mg of Vitamin C for the first 6 hours and then 3 times daily thereafter”. A control (comparison) group consisting of 463 volunteers took conventional decongestants and pain relievers. The Vitamin C users reported an 85% drop in cold and flu symptoms when compared to the conventionally treated volunteers. The authors of this observational trial concluded that, “Vitamin C in megadoses administered before or after the appearance of cold and flu symptoms relieved and prevented the symptoms in the test population compared with the control group”. A scientific paper from 2007 about avian flu suggests that the “proper use of ascorbic acid … could provide effective containment for the flu pandemic”. Further support for this hypothesis can be found in a laboratory experiment from October of 2008. In it, researchers note that Vitamin C and a form of C that is formed in the body (dehydroascorbic acid) possess direct anti-viral activity with relation to influenza virus type A. (20,21,22)
• Vitamin E - Finally, Vitamin E is perhaps the best researched antioxidant with regard to flu-related mortality. That is, at least in animals. Numerous experiments indicate that E may reduce flu complications in aged rats and, perhaps, even in younger lab animals. Some research even suggests the Vitamin E may be more effective in managing influenza than other antioxidants such as glutathione, melatonin or strawberry extract. In addition to protecting against pulmonary inflammation and reducing viral concentrations, Vitamin E also appears to decrease influenza associated weight loss in older mice. This may be relevant for senior patients who can’t afford even brief bouts of decreased food intake. (23,24,25)

Please understand that I’m not suggesting that you forego any form of appropriate medical treatment and that you opt for antioxidants instead. This is not what the new research from University of Alabama recommends nor what I am proposing. There is simply no need to take any unnecessary chances with a virus that, in the vast majority of cases, can be effectively managed. My intent in providing this information is that you simply consider it and discuss it with your health care providers. By doing so, you may open up an important line of dialogue that could influence your treatment path and the way many physicians approach this and future viral threats that will surely come.

Be well!

JP

Related posts:

1. H1N1 Flu Prevention Update
2. Swine Flu Prevention
3. Elderberry Flu Protection
4. Swine Flu, Sleep Apnea and Alzheimer’s Updates
5. Grape Antioxidants for Heart Health and Diabetes

One of the more challenging aspects of raising a child is deciding when it’s absolutely necessary to use medications. There are many factors to consider especially when the condition that needs treatment isn’t life threatening. One example is a disorder referred to as ADHD (attention-deficit hyperactivity disorder). There are several controversial and potent medications currently being used to manage ADHD symptoms. However, many allopathic physicians and parents are unaware that there are some natural alternatives that may also make a difference.

A study published in the October 20th issue of the journal Biomedicine & Pharmacotherapy may offer hope to those looking for a more natural and safer option to the drugs generally used to address ADHD. This fascinating research focused on the role that certain trace minerals play in the manifestation of ADHD symptoms. A group of scientists administered a pine bark extract (1 mg/kg/day) or a placebo for 4 weeks to 65 children and adolescents with ADHD. 56 healthy youngsters were used as a comparison group. Blood samples were taken pre and post trial that quantified the levels of copper, iron, selenium and zinc.

• Lower concentrations of zinc and higher levels of copper were found in the young participants with ADHD.
• Iron (measured as total iron, ferritin and transferrin) and selenium levels were comparable among those with ADHD and without.
• Pink bark extract supplementation was shown to reduce copper and total iron levels in the young ADHD patients.

The authors of the study concluded that pine bark “modified trace element status, normalized total antioxidant status through a decrease of Cu (copper), Fe (iron), and Cu/Zn (zinc) ratio and improved clinical symptoms of ADHD”. The improvement in the copper/zinc ratio may be an important piece to the ADHD puzzle. A separate study from April of 2009 found that adding 15 mg of zinc to the diet of 218 “third grade students” reduced symptoms of attention deficit and hyperactivity. (1,2)

Another newly published trial did not find the same level of success as the previously mentioned inquiries. The experiment was conducted at the Department of Psychiatry at the University of Medical Sciences, Arak, Iran. It tested the effects of a ginkgo biloba extract in a group of 50 boys and girls with ADHD. Over the course of 6 weeks, the young subjects were administered the ginkgo extract or a conventional ADHD medication (methylphenidate). A standardized index known as the Parent and Teacher Rating Scale was used to determine changes during the treatment period. Both groups showed some degree of improvement in the “Parent ADHD Rating Scale”. But those receiving the conventional medication improved to a significantly greater extent. The changes, as assessed by teachers, were dramatically more evident in the methylphenidate students. These findings indicate that ginkgo biloba extract, given at dosages ranging from 80-120 mg, is probably not as effective as conventional medical treatment. However, there are a few points that need to be made. Not all ginkgo extracts are created equal. It’s possible that other ginkgo extracts may perform in a more satisfactory manner. It’s also important to note that there was a higher level of reported side effects in those using methylphenidate. The adverse reactions included “decreased appetite, headache and insomnia”. (3)

The combination of turmeric extract (curcumin) and green tea may be a potent team in the fight against a variety of cancers. The most recent evidence of this is found in the October 24th edition of the journal Food and Chemical Toxicology. In that experiment, groups of lab rats were fed a conventional diet or diets that were supplemented with: a) curcumin; b) green tea catechins; or c) curcumin + green tea catechins. All of the rats receiving the herbal extracts demonstrated significant protection against the development of colon cancer. However, the combination of curcumin + green tea “displayed the most potent inhibitory effect”. The authors of the study concluded that “the combination of curcumin and catechins may produce a synergistic colon cancer-preventative effect that would be more potent than each of the compounds alone”. This same combination is also receiving attention from prestigious research outlets such as the Mayo Clinic and the M.D. Anderson Cancer Clinic with regard to chronic lymphocytic leukemia. In addition, a Chinese study from 2002 found that this duo can protect against oral cancer in an animal model. A 2007 trial even suggests that curcumin + green tea polyphenols “may have the potential to beneficially modify the life spans of animals”. (4,5,6,7,8)

Gotu Kola (Centella asiatica) has a long standing reputation for supporting mental and physical health, especially during the “twilight of our lives”. A new study presented in the journal Evidence Based Complementary and Alternative Medicine helps to strengthen the case for this traditional herbal remedy. A double-blind, placebo-controlled, randomized trial (the “gold standard” of scientific studies) recently evaluated the effects of C. asiatica in a group of 80 healthy elderly subjects. A portion of the participants received a placebo and the remainder was given varying amounts of C. asiatica (250 mg, 500 mg or 750 mg once daily) for 3 months. Physical tests and a quality of life index were administered prior to, during, and after the study.

• After 2 months of the 500 mg and 750 mg dosage of C. asiatica, participants demonstrated “increased lower extremity strength” as measured by a “30 second chair stand test”.
• These higher doses also resulted in improvements in overall “life satisfaction” and “physical function”.

The Thai-based researchers commented that the results “support the traditional reputation of C. asiatica on strength improvement, especially in the lower extremities of the elderly”. They go on to say that “C. asiatica also possesses the potential to be a natural resource for vigor and strength increase, in healthy elderly persons”. Previous experiments indicate that this herbal extract may also reduce anxiety, improve mood and enhance “working memory” in seniors. Another positive aspect to C. asiatica is its well documented ability to support healthier blood flow. This may be one mechanism by which it combats many age-related complications such as poor circulation to the brain, feet and legs. (9,10,11,12,13)

Sometimes I watch PBS, The Discovery Channel or Animal Planet and simply marvel at the things that are constantly going on in the natural world of which I am completely unaware. On some level, I understand that the ecosystems throughout the universe are burgeoning with life and activity. But what I don’t know are the details. The same is true with science. We all comprehend that there are men and women wearing white coats in some remote lab who are studying “something” that may affect us down the line. Every once in a while, a news story will appear that draws us into that elusive world. But for the most part, it’s a mysterious place. In my own small way, I hope to bridge that divide between these scientists and the rest of us “laypeople”.

Be well!

JP

Related posts:

1. Meditation for Kids with ADHD
2. Breast Cancer Protection
3. Herbs and Prostate Cancer
4. Elderberry Flu Protection
5. Fern Extract and Sun Protection

N-acetyl cysteine (NAC) is an amino acid (a component of protein) often used to support pulmonary health and protect against medication induced kidney and liver damage. It is a precursor and regenerator of a potent antioxidant in the body known as glutathione. However, several years ago a new role emerged for this natural supplement - as an adjunct in the treatment of psychiatric disorders. (1)

A few recent studies have discovered an application for NAC in the management of some very common compulsive behaviors. The first example is based on three case studies observed at the University of Melbourne, Australia. At the time, a larger study was taking place to evaluate the effects of NAC in patients with bipolar disorder. During the course of the bipolar research, it was noted that 3 patients with anxiety-based nail biting were “cured” after the administration of NAC. Another study from the University of Minnesota investigated whether NAC could help patients with a disorder known as trichotillomania, “repetitive (self) hair pulling that causes noticeable hair loss”. (2,3)

• 50 adults with trichotillomania were randomly given a placebo or NAC (1,200 - 2,400 mg daily) for 12 weeks.
• Standardized tests that assessed levels of anxiety, depression, hair pulling and psychological functioning were conducted pre and post trial.

The patients receiving NAC showed a significant reduction in hair pulling. 59% of the NAC users were “much or very much improved” as compared to 16% in the placebo group. Benefits began to appear after 9 weeks of treatment and produced no detectable adverse reactions.

A case study from 2006 in the journal Psychopharmacology also supports a connection between NAC supplementation and a decline in obsessive-compulsive disorder (OCD). In that instance, the addition of NAC to conventional antidepressant treatment improved OCD symptoms. It’s important to note that treatment with the antidepressant alone was ineffective. Only the combination of the two “medications” produced satisfactory results. The authors of the case study concluded that “further research is warranted to investigate the use of NAC and other glutamate modulating agents in the treatment of OCD”. (4)

Mental health specialists who focus on addictions are also expressing an interest in N-acetyl cysteine. Several different addictive habits appear to respond to the administration of this humble amino acid. A September 2007 study in the journal of Biological Psychiatry tested the effects of NAC in 27 “pathological gamblers”. 83% of the NAC study volunteers responded well to the treatment as compared to 29% in the placebo group. The “mean effective dose of NAC was 1,477 mg” per day. The authors of the experiment explained that NAC “might target core symptoms of reward-seeking addictive behaviors such as gambling”. They also urge for additional “larger, longer, placebo-controlled double-blind studies”. (5)

The greatest amount of research on NAC and addiction has focused on cocaine. Two trials from 2007 provide glimpses of hope for those struggling with this addition. In the first study, 23 “treatment-seeking cocaine-dependent patients” were given varying dosages of NAC (1,200, 2,400 or 3,600 mg daily) over a 4 week period. All dosage levels were well tolerated, but the higher dosages (2,400 - 3,600 mg) produced the best results. The authors noted that “The majority of the subjects who completed the study (16 of the 23) either terminated use of cocaine completely or significantly reduced their use of cocaine”. A separate study was conducted on cocaine-addicted patients in a hospital setting. 15 men and women received either a placebo or NAC during different stages of the experiment. While undergoing NAC treatment, the patients “reported less desire to use and less interest” in cocaine. (6,7)

Scientific reviews from 2008 and 2009 specifically point to NAC as a promising and safe adjunct therapy for cocaine addiction. Researchers believe that NAC may inhibit glutamate (an excitatory brain chemical) activity that prompts drug-seeking feelings. Recent laboratory trials in animal models of nicotine addiction appear to support this theory. (8,9,10)

Two of the most challenging psychiatric conditions to treat are bipolar disorder and schizophrenia. But both conditions may be responsive to NAC therapy. Thus far, it is schizophrenia that has taken the lead in NAC-based research.

A September 2008 study noted that “brain glutathione levels are decreased in schizophrenia”. The authors go on to point of that: a) NAC is known to increase brain glutathione in animal models; b) schizophrenia is often a chronic condition that is unresponsive to conventional treatment and; c) the efficacy and safety of NAC has yet to be established in humans with this condition. To help address the final point, 84 patients with chronic schizophrenia were enrolled in a double-blind, placebo-controlled study. The trial lasted a total of 24 weeks and provided either a placebo + medication or 1,000 mg of NAC + medication twice daily. The patients receiving NAC + medication demonstrated improvements in two standardized diagnostic indices: the Positive and Negative Symptoms Scale and the Clinical Global Impression Severity Scale. Those receiving NAC also exhibited reductions in a common drug-induced side effect known as akathisia, in which patients feel the need to move around in a restless manner (fidgeting, foot tapping, pacing, rocking, etc.). These results are supported by a study from August of 2008 which determined that increased glutathione levels in the brain (via NAC) may improve “auditory sensory processing” in those with schizophrenia. (11,12,13,14,15)

A recent publication in the journal of Biological Psychiatry suggests that N-acetyl cysteine may also be helpful in controlling the depressive symptoms of those with bipolar disorder (sometimes referred to as “manic depression”). Much like schizophrenia, many patients with bipolar disorder exhibit signs of “glutathione depletion” and inadequate response to conventional treatment. A trial involving 75 bipolar patients in “the maintenance phase” were treated with NAC or a placebo, in addition to their standard medicine. The study lasted 24 weeks and involved an NAC dosage of 1,000 mg twice daily. After 8 weeks of treatment, patients using the NAC showed statistically relevant improvements in daily “functioning” and quality of life scores. By week 20, the researchers also noted positive changes in depressive symptoms. The authors of the trial remarked that “NAC appears a safe and effective augmentation strategy for depressive symptoms in bipolar disorder”. (16)

While researching today’s column, I browsed through a listing of ongoing and upcoming clinical trials. I noticed that researchers from around the world are continuing to look into NACs potential with regard to alcoholism, autism spectrum disorder, combined addictions (gambling and nicotine), drug addiction and obsessive compulsive disorder. I’m very happy to see this. My sincere hope is that NAC will soon play a bigger role in the safe and sane treatment of these and other mental disorders. If you know someone who’s struggling with with a psychiatric condition, please share this information and encourage them to pass it along to their physicians as well. This is far too important information to remain hidden deep in the well of scientific literature. (17,18,19,20,21)

Be well!

JP

Related posts:

1. Sugar and Mental Health

In September 2009, I wrote about a controversy pertaining to grapefruit consumption and the relative risk of breast cancer. Since grapefruit and other citrus sources contain similar phytochemicals, I thought I should also look at the most recent information about citrus intake in general and overall cancer risk. The most current study I found is published in the October 23rd edition of the journal Cancer Causes and Control. A group of Italian researchers carefully looked for a connection between citrus fruits in the diets of patients with cancer and those without. The patients with the highest (vs. the lowest) citrus consumption were found to have:

• A 58% and 45% reduction in esophageal and laryngeal cancer.
• A 31% and 18% lower risk of stomach and colorectal cancer.

With respect to hormonally influenced malignancies, “no consistent association was found with breast, endometrial, ovarian or prostate cancer”. The authors concluded that “citrus fruit has a protective role against cancer of the digestive and upper respiratory tract”. (1)

A new population study presented in the International Journal of Cancer discovered a significantly lower risk of gastric cancer in Iranians who ate large quantities of allium vegetables (garlic, leaks, onions, etc.), citrus fruits and fresh fish. In addition, an experiment conducted in an animal model suggests that hesperetin, a phytochemical found in citrus fruits, may be a potent agent in the fight against colon cancer. (2,3)

In August and September, I wrote a two part column about the role that dietary fiber can play in the development of cancer and heart disease. The most recent issue of the journal Diabetes Care provides yet another reason why roughage should be a focal point in most healthy diets. A group of 3,428 healthy senior volunteers were followed for a period of 7 years. During that time, 162 of the participants were diagnosed with type 2 diabetes. A team of London-based researchers examined whether there might be an association between fiber consumption and the incidence of diabetes. A significantly higher risk of diabetes was found in those with the lowest fiber intake. There were also indications of higher levels of inflammation and fatty liver in those with “low cereal and low vegetable fiber intake”. (4)

There is some evidence that suggests that a high fiber diet may reduce the risk of breast cancer. One of the proposed mechanisms is that dietary roughage may effectively lower “circulating estrogen concentrations” that are believed to contribute to the risk of breast malignancies. A new study in the American Journal of Clinical Nutrition offers hope to those who are concerned about breast cancer and gives pause to those who are hoping to become pregnant. (5,6,7)

The “BioCycle Study” involved 250 menstruating women over the course of 2 cycles. Fiber intake was assessed via “24 hour recall”. Hormone levels and “incident anovulation” (failure to ovulate) were measured 8 times per cycle. It was determined that higher fiber intake reduced the levels of estradiol (a form of estrogen), follicle-stimulating hormone, luteinizing hormone and progesterone. There was also an increased likelihood of anovulation. The risk of anovulation increased in accordance with elevating levels of dietary fiber. The authors of the study concluded that, “a diet high in fiber is significantly associated with decreased hormone concentrations and a higher probability of anovulation”.

The last stop on this fiber tour relates the important role that roughage plays in supporting healthy immune function. The October 28th issue of the journal Nature describes the importance of fiber in the colon. A group of Australian researchers explain that bacteria in the colon convert dietary fiber into short chain fatty acids (SCFA), which play a vital role in immune function and suppressing inflammation. They go on to state that the highly processed diets commonly found in modern societies may be contributing to disease due to a relative lack of fiber-rich foods. (8)

I make no secret about it - I strongly believe that a daily multivitamin/mineral is a valuable tool in the promotion of overall wellness. This is all the more true for women who are planning on becoming pregnant. Three new studies illustrate several reasons why the use of an appropriate prenatal supplement is essential to the good health of mother and child.

Research from the Alcohol Research Group at the University of Berkeley, California examined “whether multivitamin supplements modify the relationship between alcohol consumption during pregnancy and the risk of miscarriage”. A total of 1,061 pregnant women participated in this analysis. The results showed that women who drank but did not use multivitamins were 67% more likely to have a miscarriage as compared to those who did not drink alcohol at all. However, women who consumed alcohol and took a daily vitamin supplement did not exhibit any increase in the risk of miscarriage. However, this information is preliminary and is obviously not a license to drink while pregnant. This is simply an illustration of the protective effect that vital nutrients can have in relation to a variety of dietary and environmental insults. (9)

Two other studies recently caught my eye. The first uncovered a long term benefit of folic acid supplementation during pregnancy and a reduced risk of “childhood behavioral difficulties” in “offspring”. Higher rates of hyperactivity and “peer problems” were noted in children born to mothers who consumed lower levels of folate during their pregnancies. These symptoms were noted in children with ages between 7 and 9. An objective measure of folate inadequacy was also detected - infants born to mothers lacking in folate exhibited a statistically smaller head circumference. The authors of the trial commented that, “lower folate status in early pregnancy might impair fetal brain development and affect hyperactivity/inattention and peer problems in childhood”. Finally, an antioxidant-rich prenatal supplement was found to provide long term heart and kidney protection for the offspring of lab rats. A particular benefit was found with regard to blood pressure regulation and a healthier circulatory system of the offspring whose mothers received key nutrients such as folate, selenium, Vitamin C and E. (10,11)

Earlier I mentioned that I’d be updating some of my previous blogs. I probably should have described my intent in a slightly different way. What I really hope to accomplish with these follow-ups is to reinforce positive habits and lifestyle choices. We all have a lot of helpful information at our fingertips these days. But with so many facts and figures swirling around, it’s very easy to misplace the very tips and concepts that we’d liked to incorporate into our daily routines. In reality, a gentle nudge and a friendly reminder is what I’m serving up today.

Be well!

JP

Related posts:

1. Dietary Fiber and Cancer
2. Dietary Fiber and Heart Disease
3. Super Fruits and Veggies
4. Multivitamins in the News
5. Rainbow Diet News

A recent study in the journal Circulation helps to clarify the well established link between excess body fat and the risk of blood clots (venous thromboembolism - VTE). A ten year observational trial followed a group of 57,054 middle-aged men and women. Measurements of body fat, hip and waist circumference and weight were taken at baseline. Other potential risk factors for VTEs were also noted - such as diabetes, high blood pressure and cholesterol, hormone replacement therapy and physical activity. Over the next decade, a total of 641 blood clotting incidents were verified via a review of medical records. After all of the data were carefully examined, it was determined that women with a higher hip circumference were at an increased risk of having blood clots. In men, a larger waist circumference was associated with more VTEs. This indicates that specific fat distribution may influence the likelihood of these potentially life threatening events. Previous studies have also identified abdominal obesity and “subcutaneous obesity” (fat located just under the skin) with increased venous thromboembolism risk. (1,2,3)

Antipsychotic medications are frequently prescribed to patients of all ages. Some psychiatrists believe this strategy is one of the best ways to stabilize individuals with a variety of mental disorders. The October edition of the Journal of the American Medical Association points out an important concern associated with the use of this class of drugs. A total of 205 children and adolescents completed the study. All of the youngsters had been diagnosed with aggressive/disruptive behavior, mood or schizophrenia spectrum disorders. The specific medications used in the 12 week study were: aripiprazole, olanzapine, quetiapine or risperidone.

• After 11 weeks of treatment, patients using aripiprazole gained approximately 19 lbs.
• Those receiving olanzapine gained about 13 lbs.
• Quetiapine users increased their weight by roughly 12 lbs.
• Risperdione patients gained just under 10 lbs.

A group of 15 patients “who refused participation or were non-adherent served as a comparison group”. The untreated children gained less than .5 lbs. On the other hand, those given olanzapine and quetiapine demonstrated increases in blood sugar, LDL (”bad”) cholesterol and trigylceride concentrations. Risperidone caused a significant elevation in triglycerides as well. These side effects caused between 10% - 36% of the young patients to be classified as overweight or obese by the end of the 11 week experiment. These alarming findings led the authors to remark that, “These medications can be lifesaving for youth with serious psychiatric illnesses such as schizophrenia, classically defined bipolar disorder, or severe aggression associated with autism. However, given the risk for weight gain and long-term risk for cardiovascular and metabolic problems, the widespread and increasing use of atypical antipsychotic medications in children and adolescents should be reconsidered.” (4)

These results do not appear to be a fluke. A prior study involving adults living in Singapore found similar results after 6 months of antipsychotic treatment. In that trial, an average weight gain of over 12 lbs was observed. Undesirable shifts in cholesterol levels were likewise reported. In addition, other research suggests that certain psychiatric patients may be more sensitive to these adverse reactions. For instance, scientists from the University of Toronto Department of Psychiatry state that women may be more susceptible to “weight gain, diabetes and specific cardiovascular risks of antipsychotics”. (5,6)

There is a growing consensus in the scientific community that being overweight predisposes men and women to inadequate vitamin D levels. A recent analysis suggests that 1 out of 2 obese men and 1 of every 3 obese women are clinically deficient in this vital nutrient. Now, an Australian study published in the American Journal of Medicine rings a new bell of alarm. 17 obese hospital patients with “severe vitamin D deficiency” were given 10,000 IUs of Vitamin D3 daily for 1 week. Blood tests were taken before and after to determine any changes in serum 25-OH D concentrations - a measure of D levels in the blood. The researchers discovered that those with the highest body mass index (BMI) responded the least to the “medication”. Therefore they concluded that “Efficacy of Vitamin D supplementation is depended on BMI. Overweight and obese patients with hypovitaminosis D might require higher doses of Vitamin D to achieve Vitamin D repletion compared with individuals with normal body weight”. (7,8,9)

Every “problem” I’ve written about today has a practical solution. Eating a more healthful diet and exercising regularly can decrease body fat accumulation and, thereby, possibly reduce the risk of blood clots. Those same changes may also help one to avoid the underlying need for certain antipsychotic medications. If those strategies aren’t enough, there are plenty of natural remedies that are known to support healthier circulation and psychological stability (fish oil, niacin, Vitamin D). Some people may still require carefully selected prescription drugs to manage their medical issues. But even if they do, simply being aware of the possible side effects can help them and their physicians to take steps to avoid such complications. It is precisely this kind of integrative approach that I hope will become the future of health care. (10,11,12,13,14,15)

Be well!

JP

Related posts:

1. Rainbow Diet News
2. Weight Loss News
3. Health News Not in the News

In the past few months there have been several promising studies about a variety of holistic treatments for chronic headaches. Please keep in mind that I’ve only selected a handful of the newest published trials. (1)

A recent survey discovered that chiropractic was the most popular alternative therapy for “chronic tension type headaches”. The problem that many physicians have with this form of treatment is that there aren’t many well designed studies that prove its efficacy and safety in those with this variety of pain. However, a new study appearing in the Journal of Manipulative Physiological Therapeutics helps to strengthen the case for chiropractic adjustments in the treatment of tension headaches.

• Participants with at least 10 tension related headaches per month were included in the research. Headache symptoms were recorded for 4 weeks prior to the trial and 14 weeks later, at its conclusion.

• Four groups were established: a) chiropractic + medication; b) chiropractic + placebo; c) sham chiropractic + medication; d) sham chiropractic + placebo.

Those receiving the combination therapy of chiropractic + medication demonstrated a significant reduction in headache frequency. While promising, the researchers are calling for additional study with a larger pool of participants. (2,3,4,5,6)

A form of body manipulation known as trigger point therapy may also benefit those with “tension-type headaches”. A recent scientific review describes trigger points as “discrete, focal, hyper-irritable spots located in a taut band of skeletal muscle”. Administering analgesic (pain relieving) injections or carefully applied massage to these locations can often relieve chronic pain. This fact is evidenced by a few recent studies. The latest of which involved 9 adolescent females with tension-type headaches. All of the participants were administered twice-weekly “trigger point specific physiotherapy”. Dramatic improvements in headache duration (77%), frequency (68%) and intensity (74%) were reported after about 7 sessions. No adverse effects were documented. A 2008 study from Spain also found impressive success rates in a larger and more diverse group of study volunteers. (7,8,9)

Kiko, a Japanese martial arts practice that involves “repetitive coordinated breath and movement”, was recently found to significantly reduce migraine symptoms in a small group of headache sufferers. Baseline and post-trial migraine symptoms were rated and recorded. The participants were taught Kiko in 3 monthly sessions and then practiced it at home using an instructional DVD. Only about half of the study volunteers completed the 4 month trial. But all of those who did experienced “measurable improvement in their migraines” with “no reported adverse effects”. I’m mentioning the relatively high “drop out” rate because this is an important consideration when choosing any kind of treatment. The fact is that many natural remedies require more effort and persistence than simply popping a prescribed capsule or tablet. (10)

Two new studies support the use of acupuncture in patients with both acute and chronic migraines. The first trial appears in the June edition of the journal Headache. 175 migraine sufferers were divided into 3 groups - a treatment group, which received verum (real) acupuncture and two “sham” acupuncture groups. The pain relieving effects of the respective treatments were measured 1/2 hour, 1 hour, 2 hours and 4 hours post application. The researchers also monitored the degree of “aggravation”, pain and relapse in the subsequent 24 hour period. The authors of the study noted that real acupuncture, “is more effective than sham acupuncture … in reducing the discomfort of acute migraine. Verum acupuncture is also clearly effective in relieving pain and preventing migraine relapse”. A separate study from April 2009 determined that directing acupuncture at the gallbladder and liver meridians (specific acupuncture points) may be more effective and safer than conventional medication in the long term (chronic) management of migraines. The patients in that trial were followed for a total of 1.5 years. (11,12)

There are some people out there who have tried numerous conventional and natural treatments to alleviate chronic headaches and have been unsuccessful. Sometimes they’ve been to the most respected experts in the field and have even tried the most rigorous alternative options available. To those individuals I say: Please don’t give up! There are always avenues that are left to be explored. An example can be found in the July edition of the Journal of Alternative and Complementary Medicine. A case study is presented about a 13 year old girl who is physiologically healthy but has been suffering from headaches since the age of 11. After a thorough holistic evaluation, a specific Japanese (Kampo) herbal remedy known as saikokaryukotsuboreito was prescribed. The young lady found acute relief as long as she remembered to take her “medicine”. After 11 months of treatment, the use of the herbal remedy was discontinued. The headache did not recur after that based on a 3 year follow up evaluation. The authors of this case study commented that, “Kampo formulas are selected not only by paying attention to the primary symptom but also by checking the other characteristics (symptoms, constitution, etc.)”. Previous experiments using another Kampo herbal medicine (goshuyuto) have also noted success in larger study groups. (13,14,15)

It’s vitally important to have options in health care. No one therapy is right for everyone - whether natural, synthetic or something in between. Human beings are not a “one size fits all” kind of organism. We’re unique in our physiological and psychological make up and, therefore, require an individualized medical approach. But if we’re not aware of the available options, they don’t practically exist. If Kampo just sounds like a foreign word and trigger point therapy brings a gun to mind, then it’s highly unlikely that you’ll ever have the opportunity to benefit from these potentially life changing treatments. This is part of the reason why I’m so happy to be able to research these and other topics and share them with you.

Be well!

JP

Related posts:

1. Acupuncture vs. Headaches
2. Natural Remedies for High Blood Pressure
3. Natural Remedies for Female and Male Hair Loss
4. B-Vitamins for Migraines
5. Nature’s Arthritis Remedies

Emerging evidence suggests that excess production of cortisol, the body’s primary stress hormone, may contribute to poor bone status in older and younger populations alike. It also appears that this proposed connection is a risk factor for both genders. But there’s even more to the story. Simply treating stress with medications doesn’t appear to improve skeletal health. In fact, some of the drugs used to address anxiety and depression may actually make things worse.

A new study in the Journal of Clinical Endocrinology and Metabolism provides a powerful example of the correlation between “hypercortisolism” and poor bone status. This Italian examination looked for an association between mildly elevated stress hormones and low bone density. 287 patients with subclinical hypercortisolism (SH) were compared to 194 healthy volunteers. Both groups contained a broad cross section of men and women of varying ages. X-rays were taken of all the participants at two relevant locations (femoral neck and lumbar spine). The researchers determined that those with high cortisol had dramatically lower bone density in the femoral neck and lumber spine regions. There was also a more than 3 times greater risk of fractures in the patients with SH. This additional risk was not influenced by factors relating to age, gender or menopausal status. (1)

There have been several other trials from 2009 that support the osteroporotic/stress connection. Each of the studies focuses on a different population group - adult men, overweight adolescents and anorexic women. This is important to note because the negative effects of stress hormones on the skeletal system can apparently impact all of these disparate groups. Therefore, the possibility exists that this unwanted side-effect could also apply to the population at large.

• A 12 month observational trial was conducted on 88 men with subclinical hypercortisolism and 90 healthy subjects. Bone mineral density and cortisol levels were measured at the start and end of the study period. Femoral neck and lumbar spine bone status was dramatically lower in those with high cortisol levels. The lumber vertebrae were found to be particularly porous, which could explain the higher “prevalence of vertebral fractures” in this sensitive group. (2)

• Anorexia nervosa (AN) is an eating disorder that is characterized by excessive cortisol production. A recent experiment conducted at Massachusetts General Hospital and Harvard Medical School examined the role that “anxiety, depression and/or cortisol dysregulation contribute to low bone density”. As expected women with AN were found to produce larger quantities of cortisol and suffer from higher levels of anxiety and depression as compared to healthy volunteers. They also exhibited lower bone density at the hip and spine. The authors of the trial concluded that, “hypercortisolism is a potential mediator of bone loss and mood disturbance”. (3)

• The National Institutes of Health recently published a study that involved 137 overweight, adolescent boys and girls. Questionnaires, specialized interviews and various diagnostic tests were performed to determine bone density, eating patterns and psychological status in the youngsters. The researchers discovered a connection between the stress caused by “adolescent shape and weight concern” and lumbar spine bone density. The association between bone health and stress was determined via the measurement of urinary cortisol and x-rays. (4)

Anxiety and depression are typically associated with elevated cortisol levels. This may explain why these psychological conditions are now proposed as an independent and substantial risk factor for low bone density. A meta-analysis from September 2009 reviewed 23 studies that compared the bone status of depressed individuals to healthy volunteers. On average, depressed men and women demonstrated weaker bones in their forearms, hips and spine regions. Women appeared to be more vulnerable to the effects of psychological distress than men. An interesting side note is that premenopausal women were at greater danger for fractures than postmenopausal women. A separate study in the journal Bone also suggests a strong correlation between depression in premenopausal women and low bone density. The authors of that research recommend that such patients “should be investigated for osteroporosis”. (5,6,7,8)

In order to investigate how stress alters bone density, researchers have looked to a condition known as Cushing’s syndrome, which features “overt hypercortisolism” and can lead to “osteoporosis and fractures in up to 70% of cases”. In such circumstances, there is a dysfunction in the mechanisms by which bones are broken down and rebuilt. There may also be some indirect ways that cortisol exacts its damage, such as altering sex hormone levels and promoting calcium malabsorption. Certain medications can also inadvertently contribute to the problem. For instance, depressed patients given anxiolytic medications (for anxiety) or antidepressants may develop weaker bones as a consequence. (9,10,11)

The information presented today may seem discouraging or otherwise gloomy in nature. Perhaps you’re even stressing out just thinking about it! Don’t! The good news is now that you’re aware of the risk of feeling chronically stressed, you can do something to change your state of mind. There are safe, natural and inexpensive remedies such as aromatherapy, fish oil, guided imagery, music therapy and yoga that are all scientifically proven to help lower cortisol levels. It doesn’t matter what you do to manage your stress levels. Just make sure that you do something to address it. Not only will you feel better, but you can also be confident in the fact that there are beneficial changes simultaneously occurring in other parts of your body as well. (12,13,14,15,16)

Be well!

JP

Related posts:

1. Vitamin C and Bone Fractures
2. Osteoporosis and Exercise
3. Soy for Strong Bones
4. Red Wine Cancer Connection
5. Acupuncture, Macular Degeneration and Osteoporosis Updates

Apitherapy is a term used to describe the therapeutic use of bee products. It may seem counterintuitive that bee venom could, should or would be used in any healing capacity. However, there is a chemical basis for this traditional form of treatment. A summary in the current issue of Apitherapy Review explains that bee venom possesses “a strong influence on the nervous and circulatory systems”. The author of the piece, Prof. Roch Domerego, goes on to summarize a host of other documented benefits that include anti-inflammatory activity and immune system support. (1,2,3)

There are many anecdotal reports of dramatic healing via apitherapy. A letter published in the November issue of Natural Health magazine is one of the most recent, publicized cases of bee venom success. In it, the wife of a multiple sclerosis (MS) sufferer explains that her husband has been using bee venom therapy (BVT) “to decrease the frequency, strength, and duration of his (MS) flare ups, and to increase his energy levels”. This letter to the editor piqued my interest. I wondered what scientific evidence exists that supports the use of medical apitherapy. Here’s what I found:

Both osteo and rheumatoid arthritis appear to be somewhat responsive to bee sting therapy. A study from June 2008 determined that a combination of apitherapy and conventional medication lead to statistically better outcomes in a group of 50 patients with rheumatoid arthritis. Greater declines in pain, stiffness and swelling were among the benefits noted. There was also a significant drop in the “relapse rate” in those using bee venom (12% vs 32%). A 4 week trial in patients with osteoarthritis used “pain relief scores and computerized infrared thermography” as a means of evaluating the success rate of apitherapy. In this case the bee venom prevailed over a course of “traditional needle acupuncture”. In addition, a March 2005 review in the journal Evidence Based Complementary and Alternative Medicine examined the results of 15 trials focusing on bee venom acupuncture (BVA) and arthritis. The conclusion was that more research was certainly called for but that “it is highly likely that the effectiveness of BVA for arthritis is a promising area of future research”. (4,5,6)

Administering bee venom to well established acupoints (relevant acupuncture locations) may be partially responsible for the success of these therapies. A study in an animal model discovered that injecting bee venom into therapeutic acupoints resulted in greater pain reduction as opposed to the same treatment given in “non-acupoint” injection sites. Furthermore, an April 2008 meta-analysis in the Journal of Pain investigated the efficacy of bee venom acupuncture in conditions such as “arthritis, pain and rheumatoid diseases”. A total of 11 randomized clinical trials was the basis for the review. The authors concluded that the “results provide suggestive evidence for the effectiveness of BVA in treating musculoskeletal pain”. (6,7,8)

The newest human study available on apitherapy involves its use in managing low back pain. A total of 150 patients with “chronic lumbar muscle strain” participated in the trial. Half were provided with routine acupuncture, while the remainder was treated with diluted bee venom in the same acupoint locations. All of the patients received a total of 30 sessions of the respective acupuncture modalities. Six months later, both groups were analyzed to establish treatment outcomes:

• The bee therapy group (78 participants in all) reported 49 cured patients, 27 improvements and 2 “ineffective” results. This is a “cured rate” of 63%.
• The conventional acupuncture group (72 cases) yielded 29 cures, 40 improvements and 3 “infective” results. This equals a “cured rate” of 40%. (9)

Perhaps the most controversial application of apitherapy is in patients with multiple sclerosis (MS), an autoimmune condition which causes nerve damage and, thereby, interferes with the brain’s ability to communicate with the body. According to an article in the September 2007 edition of Neuropharmacology, there is a “renewed interest in the therapeutic potential of venoms in MS”, but the “efficacy of this therapeutic method remains unclear”. The uncertainty has a lot to do with: a) mixed results in a limited number of scientific studies and; b) numerous anecdotal reports of successful treatment. (10)

For all intents and purposes, there are two human studies that are available for evaluation. The first was published in December 2005 in the journal Neurology. A group of 26 patients with MS underwent 24 weeks of bee sting therapy or no therapy on separate occasions. MRIs were used to determine the number of MS-related brain lesions prior to and after each phase of the study. Various standardized scales were also employed to measure disability, fatigue, relapse rates and quality of life. The bee sting therapy involved 3 sessions per week with a maximum 20 stings per appointment. At the end of the “crossover” study, the researchers concluded that there was no benefit found during the apitherapy phase of the study. The bee venom didn’t improve MS symptoms nor slow down disease progression or relapse time. (11)

Another study from 2005 found slightly more encouraging results. Researchers from Georgetown University tested the efficacy and safety of a bee venom extract in 9 patients with MS. 4 of the 9 patients dropped out of the study before its completion. However, of the 5 remaining participants, 3 reported “subjective” symptomatic improvements. 2 of the MS patients demonstrated objective measures of disease improvement - based on “functional neurological tests” and standardized questionnaires. The authors of this experiment concluded that “this preliminary study suggests safety”, but went on to add that “larger and more carefully controlled multicenter studies will be required to establish efficacy”. (12)

Scientists such as Dr. Robert Zurier of the University of Massachusetts Medical School have been studying bee venom for over 30 years. Because of his efforts and the valuable contributions of others, the underlying mechanisms by which bee venom “works” is becoming clearer. However, the march of progress is far too slow for those who are suffering here and now. There is a desperate need to establish how and why apitherapy is effective for some people with presumably “incurable” and/or “unresponsive” conditions. Until that day comes, it’s important for us as health care consumers to weigh our options very carefully. Please be aware that bee venom therapy is a largely unregulated practice. Therefore, I think it’s absolutely vital to seek out the best possible references before giving it a shot. (13,14,15)

Be well!

JP

Related posts:

1. Dr. Oz and Sauna Therapy
2. Acupuncture vs. Headaches
3. Animal Assisted Therapy
4. Aquatic Therapy
5. Autism and Hyperbaric Oxygen Therapy

I recently tried an herbal product that has helped me through a particularly stressful period in my life. In the past, I’ve experimented with a variety of nutritional supplements that are intended to promote a “healthy mood”. Many of these formulations attempt to balance adrenal gland function and brain chemistry in order to ease anxious feelings and promote a more optimistic perspective. These natural alternatives also strive to avoid the common side effects associated with prescription medications that are used for the same purpose.

The Product - Natural Factors’ Serenity Formula

Serenity Formula is recommended by Michael Murray, a highly regarded naturopathic physician. The “structure/function” claim on the label states that this product “promotes emotional well being” and further describes it as “a unique combination of herbal extracts that help the body cope with stress”.

Serenity Formula - Dosage and Ingredients

The supplement provides: 250 mg of a patented Ashwagandha extract (Withania somnifera) known as Sensoril. It also features 150 mg of standardized extracts of Eleuthero (”Siberian ginseng”), 150 mg of Lavender extract and 75 mg of Rhodiola rosacea. The recommended dosage is 1 capsule twice daily. That dosing pattern will provide the quantities listed above. A higher dosage of 2 capsules twice daily can also be implemented if required.

The Science Behind Serenity Formula

Ashwagandha, the primary ingredient in the herbal blend, has a long history in traditional Indian medicine of supporting mental health. Recent scientific inquiries indicate that it may be a useful tool in the management of anxiety, cognitive decline, depression, drug addiction and a variety of neurological conditions. There’s even a study underway that’s examining its effects in patients with bi-polar disorder. Eleuthero and Rhodiola are typically classified as “adaptogens”, substances that assist the body to safely adapt to physical and psychological stressors. Lavender’s effect on mood tends to be associated with its lovely fragrance. Specifically, essential oils from lavender flowers have been historically used as a calming agent. But there is also some preliminary evidence that suggests that lavender consumption can provide an anxiolytic (anti-anxiety) and antidepressant effect. (1,2,3,4,5,6,7,8,9,10,11)

My Personal Experience with Serenity Formula

I started using the lowest recommended dosage for the first week (1 capsule 2x day). I almost always suggest beginning slowly with any new supplement. My initial impression was that I was experiencing some degree of a “mellowing” reaction. I also noted that this calming sensation did not bring about any daytime sleepiness or grogginess. As an experiment, I decided to increase my intake on the second week to 2 capsules 2x a day. This seems to work more effectively for me. But please keep in mind that I’m a rather large fellow - 6 feet tall and 180 pounds.

Additional Observations and Tips

A pet peeve of mine is when supplement manufacturers don’t give precise recommendations in the “Suggested Usage” portion of a product label. For instance, the directions for Serenity Formula omit whether it should be taken on an empty stomach or with food. I did however place a call to Natural Factors’ Canadian office and was told that taking it on an empty stomach would be preferable, unless doing so caused digestive upset. For about 3 weeks now, I’ve been taking 2 capsules between breakfast and lunch and again between lunch and dinner. It hasn’t upset my stomach yet.

Naturopathic Care (NC) vs. Psychotherapy (PT) - Beck Anxiety Inventory Results

Concluding Remarks on Serenity Formula

While putting together today’s product review, I visited several online supplement providers. Many Internet based “health food stores” allow their customers to submit brief reviews of products that they’ve tried in order to better inform other customers. Serenity Formula seems to be very well received by most of the people who’ve actually tried it. This is reassuring because my report is purely anecdotal in nature. However, I want to point out that I’m a rather tough customer with regard to mood altering supplements. I generally don’t respond to them at all. That’s part of the reason why I wanted to highlight this particular herbal formula. Simply stated, it worked for me.

One of the best aspects of natural medicines is that they often provide “side benefits” instead of side effects. In this instance, Ashwagandha can improve fertility and immune function during stressful times. Eleuthero and Rhodiola may “increase mental performance and physical working capacity in humans”. Likewise, lavender may one day “provide the key to eradicating degenerative inflammatory disease, infectious disease, and carcinogenesis” according to some researchers. Natural foods and medicinal herbs are multi-taskers. When they’re used judiciously, they have great potential for improving specific symptoms and overall quality of life. (12,13,14,15,16)

Be well!

JP

Related posts:

1. Coromega - Product Review
2. Chocolate Green SuperFood - Product Review
3. Arctic Root Energy

Two newly released studies have implications for those undergoing cancer treatment. A systemic review in the November 2009 issue of Breast Cancer Research and Treatment examines the use of acupoint stimulation as a means of reducing “therapy-related adverse effects”. A total of 26 studies were included in the review. 23 of the trials reported successful outcomes. Acupressure, electro-acupuncture, magnet-assisted acupoint therapy and traditional acupuncture were the modalities utilized in the positive experiments. According to the authors of the summary, the stimulation of a specific acupressure point known as P6 (NeiGuang) appears to reduce chemotherapy related nausea and vomiting. (1)

A Turkish study from September 2009 tested this same acupoint in a group of 34 patients with “gynecologic cancer”. In this case, a wristband that applies consistent pressure to the P6 point was worn by patients undergoing chemotherapy. The addition of the wristband decreased the severity of nausea and reduced the amount of medication (antiemetics) used to control nausea related side effects. A decline in “retching episodes” and vomiting was also established, though to a smaller degree. The concluding remarks of the scientists indicate that “acupressure applied to P6 acupuncture point with wristbands may be effective in reducing chemotherapy related nausea and may decrease the antiemetic use after chemotherapy”. (2)

The reach of acupressure extends far beyond just serving as an adjunct to cancer treatments. For instance, applying 30 minutes of pressure to a pressure point known a SP6 (Sanyinjiao) located just above the ankle may help reduce “the duration and severity of pain of the active phase of labor, cesarean section rates and necessity and amount of oxytocin” (a hormone/medication which induces labor). New evidence also points to a role that acupressure may play in the long term management of type 2 diabetes. A 3 year study recently compared the effects of diet and lifestyle modification in a group of 80 diabetics. Half the group received frequent acupressure therapy (AT) in addition to standard care. The AT diabetics demonstrated lower levels of LDL (”bad”) cholesterol and triglycerides, higher levels of HDL (”good”) cholesterol and exhibited signs of healthier kidney, liver and nerve function. This difference seems to be directly attributable to the effect of acupressure alone or in concert with diet and exercise. (3,4)

Massage can also have a powerful impact on serious conditions such as breast cancer. A recent Swedish study examined the immune function of a group of 30 middle-aged women with breast malignancies. All the women were undergoing radiation therapy at the time of the experiment. Half of the group began a complementary course of “light pressure” massage while the remainder acted as the control group. Blood and saliva samples, blood pressure and heart rate were measured before and after each massage session. The researchers discovered that the massage group maintained better immune function (natural killer cell activity) and showed a reduction in heart rate and systolic blood pressure. (5)

Sometimes scientists set out to study one thing and they end up uncovering something quite unexpected. In October 2009, a paper was presented in the journal Multiple Sclerosis. The intention of the researchers was to test the efficacy of a type of massage known as reflexology on the pain stemming from multiple sclerosis. Reflexology involves the careful manipulation of pressure points on the sides and soles of the feet. In this trial, two types of massage were applied to a group of 73 MS patients. One group received the legitimate form of reflexology, while the others were given non-specific foot massages. Pain measures were taken pre, mid-way and post trial using a scientifically accepted index known as a Visual Analogue Scale (VAS). Much to the researchers’ surprise, both groups exhibited significant reductions in depression, disability, fatigue, pain and spasms. The participants also reported a generalized improvement in their perceived quality of life. (6)

Combining massage with other therapeutic practices is also gaining ground in medical circles. Adding massage to conventional psychotherapy was recently shown to improve depression in prenatal women. A study performed at the University of Miami School of Medicine found that adding 20 minutes of massage therapy to a normal 60 minute session of “Interpersonal Psychotherapy” brought about greater reductions in anxiety, depression and stress hormone levels (cortisol). (7)

The addition of massage therapy to an exercise program can likewise improve the outcome of physiological conditions. A trial just published shows that exercise plus massage can dramatically improve the health of patients with a painful leg condition known as peripheral arterial disease (PAD). Beneficial changes in blood pressure and circulation were noted in the lower extremities of those engaging in this two-pronged treatment protocol. (8)

Acupressure and massage can support physical and psychological wellness by enhancing circulation and immune function, lowering blood pressure, pain, stress hormones, and even prompting the release of endorphins (the brain’s “feel good” chemicals). These types of treatments also connect us in a rather intimate way to another caring individual. Over the course of 60 minutes or so, you’re literally in the hands of a healer whose sole purpose is to help you regain your good health. It’s not often that we can allow ourselves to simply let go and become the center of attention in a genuinely constructive way. I would really love for such mind-body therapies to play a larger role in 21st century medicine. I believe the best way for that to happen is for us, as consumers and patients, to request it. Think of the possibilities - fewer drugs and more massages. Sounds good to me!

Be well!

JP

Related posts:

1. Acupressure for Health
2. Massage for Anxiety and Pain
3. Health News Not in the News