Promega Profiles in DNA Articles

Database Process Automation Using DNA IQ™, Plexor® HY and PowerPlex® 16 HS Systems on the Biomek® 3000 Workstation

Fri, 26 Aug 2011 09:34:17 -0500

In this article, Cyndi Cunnington from the Idaho State Police Forensic Services Laboratory describes the lab's experience to evaluate the Promega Identity Automation™ methods for DNA IQ™ extraction, Plexor® HY setup, sample normalization and PowerPlex® 16 HS amplification setup on the Beckman Coulter Biomek® 3000 workstation.

Allele Frequencies for Penta C in Caucasian, African American, American Indian, Asian and Hispanic Populations

Thu, 25 Aug 2011 10:29:40 -0500

This study presents Penta C allele frequencies for Caucasian, African American, American Indian, Asian and Hispanic populations.

Newest Members of the Genetic Identity Team

Mon, 18 Jul 2011 10:20:53 -0500

Promega introduces the newest Genetic Identity team members: Rohaizah James and Jon Drobac.

The Latest and Greatest NIST PCR-Based DNA Profiling Standard: Updates and Status of Standard Reference Material® (SRM) 2391c

Thu, 14 Jul 2011 16:16:20 -0500

In this article, NIST scientists introduce the new Standard Reference Material® 2391c (SRM 2391c) PCR-Based DNA Profiling Standard. This is the third renewal of this SRM, originally released in 1995 and consists of six components, labeled A through F.

New Control DNA for PowerPlex® Systems

Wed, 13 Jul 2011 16:27:46 -0500

Promega is replacing the 9947A DNA and 9948 Male DNA provided in PowerPlex® Systems with 2800M Control DNA beginning in 2012. This new control DNA is a single-source male human genomic DNA purified from blood. Because it is a male DNA, the control DNA is appropriate for use with all PowerPlex® Systems.

Forensic DNA Profiles Crossing Borders in Europe (Implementation of the Treaty of Prüm)

Fri, 08 Jul 2011 12:35:32 -0500

In this article, Kees van der Beek discusses the scope of the treaty of Prüm, its implementation status, the software used for the exchange of DNA profiles, Prüm inclusion and matching rules, different types of matches that are produced, the results obtained, prevention of false-positive matches and detection of false-negative matches.

Analysis of PowerPlex® Systems using the Applied Biosystems 3500 and 3500xL Genetic Analyzers

Wed, 16 Mar 2011 16:51:41 -0500

In this Technical Tips article, Dawn Rabbach answers your frequently asked questions about how to analyze PowerPlex® reactions on the new Applied Biosystems 3500 and 3500xL Genetic Analyzers.

Mixture Interpretation: Why is it Sometimes So Hard?

Wed, 16 Mar 2011 16:13:18 -0500

Interpretation of mixed DNA profiles can be simple and straightforward in some scenarios. However, certain factors (e.g., increasing relatedness or number of shared alleles, increasing the number of contributors or disparity in the amount of DNA from each source, an increase in degradation or presence of artifacts) will likely make mixture interpretation more complex. A combination of several factors generally confounds interpretation significantly.

Shovel Away Your DNA Backlog with Lean Six Sigma Tools

Wed, 16 Mar 2011 13:06:35 -0500

The Laboratory Lean Six Sigma Practices improvement model shows real gains in production and efficiencies in forensic laboratories, without terminating or hiring staff and without adding any new diagnostic equipment.

Toward Continent-Wide Integration: A Latin American Meeting at the 21st International Symposium on Human Identification

Wed, 16 Mar 2011 12:50:10 -0500

To learn about each country's development and to stimulate a closer interaction between forensic and paternity lab experts from Latin America, a Spanish- and Portuguese-speaking working group meeting was organized by Promega Corporation during the 21st International Symposium on Human Identification.

The PowerPlex® 18D System: A Direct Amplification STR System with Reduced Thermal Cycling Time

Wed, 16 Mar 2011 11:20:13 -0500

The PowerPlex® 18D System simplifies and accelerates STR typing for database and paternity testing. With 18 loci the system is compatible with existing databases, allowing maximum data sharing between CODIS laboratories and future results to build on those databases. In addition to significant time and labor savings through robust direct amplification and rapid PCR, the PowerPlex® 18D System has the flexibility and performance to accommodate the sample types currently submitted to laboratories and successfully meet laboratory goals.

Implementation of the PowerPlex® 18D System in a Databasing Laboratory: Transforming Operations to Improve Efficiency

Wed, 16 Mar 2011 10:00:00 -0500

In this article, Julie French presents Michigan State Police's experience with an improved amplification chemistry that allows direct amplification of blood or buccal punches, and reduces cycling time to less than 90 minutes.

Newest Members of the Genetic Identity Team

Wed, 16 Mar 2011 09:04:33 -0500

Promega introduces the newest Genetic Identity team members: Jakub Gruchota, Saif Al-Badawi and Ann MacPhetridge.

The 22nd International Symposium on Human Identification

Wed, 16 Mar 2011 08:56:10 -0500

The 22nd International Symposium on Human Identification will be held October 3–6, 2011, near Washington, D.C. Workshops are planned on issues of critical importance to today’s forensic scientists including: familial searches, forensic DNA phenotyping, troubleshooting common laboratory problems and more.

Introducing the forensicCONNECT™ Online Resource

Tue, 15 Mar 2011 13:48:41 -0500

The forensicConnect™ resource reviews hundreds of daily news sources to provide relevant DNA-typing news and helpful online resources all in one place.