pharma world

Guide to Microbiological Control in Pharmaceuticals and Medical Devices

noreply@blogger.com (◄◄▌┼ÅŚ╠╣uтσŚ╠╣ รٱภg╠╣┼▐►►) — Wed, 14 Dec 2011 05:55:00 +0000

Stephen P. Denyer, Rosamund M. Baird, "Guide to Microbiological Control in Pharmaceuticals and Medical Devices, 2nd Edition"
|504 pages | PDF | 6,3 MB

Microbiological matters continue to exercise considerable influence on product quality. In both the pharmaceutical and medical device industries, products of greater sophistication, along with evolving regulatory requirements, are elevating the challenges related to maintaining microbiological integrity.

Updated to reflect technological and regulatory changes, the Guide to Microbiological Control in Pharmaceuticals and Medical Devices, Second Edition covers thoseprincipal aspects of microbiology that arerelevant to the preformulation, formulation, manufacturing, and license application stages involved with the production of pharmaceuticals and medical devices.

In recognition of the diverse disciplines involved in pharmaceutical and medical device production, this work provides a brief introduction to microbiology geared towards the nonmicrobiologist. Covering good manufacturing practice in the control of contamination, the text explores quality control, the preservation of formulations, and principles of sterilization, including microbiological-specific considerations for biotechnological products and other medical devices. It also provides additional materials on package integrity and contamination risks in clean rooms.

The editors have produced a companion text, the Handbook of Microbiological Quality Control in Pharmaceuticals and Medical Devices (see reverse), which when paired with the Guide offers a complete theoretical and practical treatment of microbiological control.

This book provides a comprehensive distillation of information concerning methodology and regulations that would otherwise remain scattered throughout the literature. It allows scientists from many fields to address potential problems in advance and implement suitable strategies at the earliest stages of development.

link:-http://www.filesonic.in/file/4153293655

Medical Pharmacology at a Glance

noreply@blogger.com (◄◄▌┼ÅŚ╠╣uтσŚ╠╣ รٱภg╠╣┼▐►►) — Thu, 11 Mar 2010 09:59:00 +0000

"Medical Pharmacology at a Glance" is one of the most renowned undergraduate texts in the field of medical pharmacology. Following on from the success of the previous three editions, Professor Michael Neal, one of the great teachers of medical pharmacology, has extensively revised and updated the fourth edition to take account of the rapid developments in the field. This incredibly useful book summarises the core principles of the mode of action of drugs and puts this information within the context of body systems and specific clinical problems. The author discusses the mechanisms of action of each drug, indicating the therapeutics of choice for specific conditions. "Medical Pharmacology at a Glance" follows the now familiar, easy-to-use double page spread format of the at a Glance series. Each section contains a clear illustration depicting the major drugs and their interaction within a particular body system and a concise account of the topic. Key features of the fourth edition include: new material on anti-platelet drugs in the cardiovascular section; new section on immunological drugs; new material on general anaesthetic and anti-viral drugs; and the use of Recommended International Non-proprietary Names (rINN) for drugs. "Medical Pharmacology at a Glance" is ideal for pharmacology revision and for use during clinical placements. It is an essential buy for medical students and scientists requiring a succinct and lucid account of medical pharmacology.

link:-http://rapidshare.com/files/168428618/tmed_pharmaco_aag.zip

Clinical Pharmacokinetics: Concepts and Applications

noreply@blogger.com (◄◄▌┼ÅŚ╠╣uтσŚ╠╣ รٱภg╠╣┼▐►►) — Thu, 11 Mar 2010 09:50:00 +0000

Since pharmacokinetics can greatly affect how different patients respond to the same drug, both students and physicians need a basic clinical understanding of this vital area. The Third Edition of "Clinical Pharmacokinetics" provides a practical perspective, with these added features: considerations of both stereochemistry and the increasing number of polypeptide and protein drugs being developed; the range and number of problems at the end of each chapter has been expanded; a second color added to make the text more user friendly; and, important equations highlighted by shading.

link:-http://rapidshare.com/files/202236399/tclin_pharmacok_ca.zip

Pharmacy Case Studies

noreply@blogger.com (◄◄▌┼ÅŚ╠╣uтσŚ╠╣ รٱภg╠╣┼▐►►) — Thu, 11 Mar 2010 09:47:00 +0000

First edition
Edited by Soraya Dhillon - Head , The School of Pharmacy, University of Hertfordshire and Rebekah Raymond - Teacher Practitioner

Pharmacy Case Studies offers a holistic and integrated approach to learning, which textbooks often lack. Case studies of increasing complexity tie in the strands of learning from across the pharmacy curriculum. Primarily aimed at pharmacy students and pre-registration pharmacists, this book will also be useful for qualified pharmacists as well as medical students, nurses and others with a professional interest in therapeutics.

Each chapter contains five case studies with questions and answers increasing in complexity from those for first year students through to cases designed for fourth year/pre-registration level. The chapters loosely follow the order of the British National Formulary chapters for eahttp://www.pharmpress.com/shop/ProductImagesse of use. Case study scenarios include both community and hospital pharmacy situations as suited to the disease and pharmaceutical care provision.

Contents:
1. Gastrointestinal: 2. Cardiovascular: 3. Respiratory: 4. CNS: 5. Infections: 6. Endocrine: 7. Obstetrics, Gynaecology and UTI: 8. Malignant Disease: 9. Nutrition and Blood: 10. Musculoskeletal and Joint: 11. Eyes: 12. ENT: 13. Skin: 14. Immunological/vaccines: 15. Liver Disease: 16. Renal Diesase: 17. Paediatrics: 18. Elderly:

link:-http://www.megaupload.com/?d=N33GBULX

Pharmaceutics: The Science of Dosage Form Design

noreply@blogger.com (◄◄▌┼ÅŚ╠╣uтσŚ╠╣ รٱภg╠╣┼▐►►) — Sun, 21 Feb 2010 18:16:00 +0000

A comprehensive textbook covering the design of dosage forms and all aspects of drug delivery systems. 'Pharmaceutics' in its broadest sense is the 'art of the apothecary' or, in simple terms, pharmaceutical preparations. It remains a diverse subject in the pharmacy curriculum, encompassing design of drugs, their manufacture, and the elimination of micro-organisms from the products. This books encompasses all those areas and pays particular attention to the design of dosage forms and their manufacture.

link:-http://rapidshare.com/files/259366987/tpharm_sci_dfd2ed.zip

Handbook of Pharmaceutical Excipients, 6th Edition

noreply@blogger.com (◄◄▌┼ÅŚ╠╣uтσŚ╠╣ รٱภg╠╣┼▐►►) — Thu, 04 Feb 2010 07:17:00 +0000

Pharmaceutical packaging is regarded as an integral part of the end pharmaceutical/drug product. Pharmaceutical Packaging Technology is structured to meet the needs of the global market, and assesses a wide range of current knowledge, catering for the requirements of the pharmaceutical industry as well as for pharmaceutical companies in emerging nations who are still seeking a basic grounding in the subject. The author integrates information on many drug delivery systems, where the packaging is an essential component of the product, to produce a book for all those dealing with the topic.

Download
http://rapidshare.com/files/149295092/tpharma_pck_tech.zip

gpat 2010

noreply@blogger.com (◄◄▌┼ÅŚ╠╣uтσŚ╠╣ รٱภg╠╣┼▐►►) — Fri, 08 Jan 2010 07:07:00 +0000

GPAT-2010

CONTENTS

1. GENERAL INFORMATION .......................................................................................................................... 2

1.1. ADMINISTRATIVE INSTITUTES…………............................................................................................................ 2

1.2. GPAT QUALIFICATION……………................................................................................................................... 2

1.3. ELIGIBILITY ................................................................................................................................................... 2

1.4. EXAMINATION SCHEDULE AND CITIES........................................................................................................... 2

1.5. APPLICATION SUBMISSION PROCESS.............................................................................................................. 2

1.6. OTHER INFORMATION…………………………………………………………………………………….... 3

2. POSTGRADUATE ADMISSIONS WITH MHRD SCHOLARSHIP ........................................................

3. STRUCTURE OF GPAT - 2010 ……….. ..................................................................................................... 3

3.1. EXAMINATION TYPE...................................................................................................................................... 3

3.2. GPAT RESULTS AND SCORECARD……………................................................................................................. 4

3.2.1. GPAT RESULTS…………….…………………………………………………………………………... ..4

3.2.2. GPAT SCORECARD …………….................................................................................................................4

4. INSTRUCTIONS FOR FILLING AND SUBMISSION OF APPLICATION FORM............................... 4

4.1. IMPORTANT INFORMATION………………………………………………………………………………………………………..4

4.2. INSTRUCTIONS FOR FILLING APPLICATION FORM AND ACKNOWLEDGEMENT CARD ......................................4

4.2.1. GENERAL ................................................................................................................................................4

4.2.2. ITEMWISE INSTRUCTIONS FOR FILLING APPLICATION FORM ....................................................................5

4.2.3. FILLING OF ACKNOWLEDGEMENT CARD..................................................................................................7

4.3. AUTHORITIES EMPOWERED TO ISSUE CERTIFICATES.......................................................................................7

4.3.1. SC/ST CATEGORY ……………………………………………………………….………………..…...7

4.3.2. PD CATEGORY …………………………………………………………………………………….…...7

4.3.3. OBC (NON CREAMY LAYER)……………………………………………………...………………….…7

4.4. FILLING AND SUBMISSION OF APPLICATION ENVELOPE .................................................................................7

ANNEXURE – I : SYLLABI FOR GPAT PAPER…………............................................................................10

ANNEXURE – II: CODES FOR FILLING GPAT APPLICATION FORM………….................................12

A. CODES FOR EXAMINATION CITIES.......................................................................................................12

B. CODES FOR STATES/ UNION TERRITORIES OF PERMANENT RESIDENCE .............................13

1. General Information

Graduate Pharmacy Aptitude Test (GPAT - 2010) is an all India examination conducted by The M S University of Baroda, Vadodara on behalf of All India Council for Technical Education.

1.1. Administrative Institute

The M S University of Baroda, is the sole authority for conducting the examination and declaring the results for the year 2010.

1.2. GPAT Qualification

Admission to postgraduate programmes with MHRD and other government scholarships/assistantships in pharmacy colleges/institutes is open to those who qualify through GPAT. GPAT qualified candidates with Bachelor’s degree in Pharmacy are eligible for admission to Master/Doctoral program in Pharmacy. To avail the scholarship, the candidate must secure admission to such a postgraduate programme, as per the prevailing procedure of the admitting institution. However, candidates with Master’s degree in Pharmacy may seek admission to relevant PhD programmes with scholarship/assistantship without appearing in the GPAT examination.

Some institutions specify GPAT qualification as mandatory even for admission of self-financing students to postgraduate programmes. GPAT qualified candidates are also eligible for the award of Junior Research Fellowship in CSIR Laboratories and CSIR sponsored projects.

1.3. Eligibility

The following candidates are eligible to appear for GPAT:

Bachelor’s degree holders in Pharmacy (4 years after 10+2) and those who are in the final year

1.4. Examination Schedule and Cities

GPAT - 2010 Examination is as per the following details:

IMPORTANT DATES FOR GRADUATE PHARMACY APTITUDE TEST (GPAT) - 2010

Issue of application forms and information brochures at designated Bank of Baroda counters or by post from The M S University of Baroda, Vadodara

18th January - 2010

(Monday)

Last date for receipt of requests at The M S University of Baroda, for issue of application material by post / at Bank counters

20th February - 2010

(Monday)

Last date for receipt of completed OMR Application form along with Pay-in - slip and Demand Draft at the organizing institute The M S University of Baroda.

18th March - 2010

(Monday)

Date of GPAT – 2010

2nd May - 2010

(Sunday)

Announcement of the results of GPAT-2010

At 17.00 Hrs

On 24th May - 2010

(Monday)

GPAT Examination: Examination will be similar to that of GATE Examination of the previous years, where the candidate will mark the correct answer out of four options in an Optical Response Sheet (ORS) by darkening the appropriate bubble.

1.5. Application Submission Process

The application fee is Rs. 1000 for General/OBC Category candidates and Rs. 500 for SC/ST/PD* Category candidates. The application fee is non-refundable.

*Person with Disability

1.6. Other Information

a) Candidates can appear in the examination only against valid admit cards. If they do not receive the same by 12th April 2010 (Monday), they should contact the Co-ordinator, GPAT, The M S University of Baroda, Vadodara.

b) The M S University of Baroda, has the authority to decide the qualifying score for the paper. In case any claim or dispute arises in respect of GPAT 2010, it is hereby made absolutely clear that the Courts and Tribunals in Vadodara and Vadodara alone shall have the exclusive jurisdiction to entertain and settle any such dispute or claim.

For information, announcements and results, visit the website listed below.

The M S University of Baroda, Vadodara http://www.msubaroda.ac.in/, www. GPAT???

2. Postgraduate admissions with MHRD scholarship

2.1. As per the directives of the Ministry of Human Resource Development (MHRD), Government of India, the following procedure is to be adopted for admission to postgraduate programmes (Master and Doctoral) with MHRD scholarship/assistantship. The GPAT performance of the candidate will be considered for admission. If the candidate is to be selected through interview for post graduate programmes, minimum 70% weightage is to be given to the GPAT performance. The remaining weightage (30% maximum) can be given to the candidate’s academic record/performance in interview. The admitting institution will prescribe minimum passing percentage of marks in the interview. Some colleges/institutes specify GPAT qualification as the mandatory requirement even for admission without MHRD scholarship/assistantship.

2.2. Candidates are advised to seek details of admission procedures and availability of MHRD scholarship/assistantship from the concerned admitting institution. The criteria for post graduate admission with scholarship/assistantship are different for different admitting institutions. GPAT office will not entertain any enquiry about admission and award of scholarship/assistantship.

2.3. It is the responsibility of the admitting institution to award the MHRD scholarship/assistantship to only those candidates who are GPAT qualified. The management of the postgraduate scholarship/assistantship is also the responsibility of the admitting institution. The M S University of Baroda has no role in the award or disbursement of scholarship/assistantship. Reservation of seats under different categories is as per the policies and norms prevailing at the admitting institution and Government of India rules.

2.4. A candidate declared “GPAT qualified at the time of admission” is entitled for MHRD fellowship for 24 months unless he/she looses it due to poor performance in the registered programme.

3. Structure of GPAT 2010

3.1. Examination Type

The GPAT examination consists of a single paper of 3 hours duration, which contains 100 questions carrying a maximum of 100 marks. The question paper will consist of only multiple choice objective questions. Each question will have four choices for the answer. The candidates will have to mark the correct choice on an Optical Response Sheet (ORS) by darkening the appropriate bubble against each question. There will be negative marking for each wrong answer that is 1/3 (one-third) mark will be deducted.

3.2. GPAT Results and Scorecard

3.2.1. GPAT Results

a. GPAT 2010 results will be announced on May 24th 2010 17:00 hrs at GPAT office. The results will also be available on the website, as listed in Section 1.6.

b. GPAT 2010 score is valid for ONE YEAR from the date of announcement of the results.

c. The machine-gradable Optical Response Sheets (ORS) are graded and scrutinized with extreme care. There is no provision for regrading and retotalling. No photocopies of the machine-gradable Optical Response Sheets (ORS) will be made available. No correspondence in this regard will be entertained.

3.2.2. GPAT Scorecard

GPAT scorecard will be made available in the website at an appropriate time. Qualified candidates will get one printed score card.

4. Instructions for filling and submission of Application Form

4.1. Important Information

a) Before you start filling the Application Form, please check that the Application Number printed on (i) Application Form, (ii) Acknowledgement Card and (iii) Envelope are the same. Any discrepancy should be brought to the notice of the Co-ordinator, GPAT.

b) It is essential to quote the Application Number in all future correspondence. The candidates are advised to keep a copy of the filled Application Form.

c) The Application Form must be folded only along the original fold line. Nothing should be stapled or pinned to it. The Barcode on the Application Form should not be tampered. The Application Form will be declared defective if these instructions are not followed.

d) Change of Examination City is permitted, only if a request for the same reaches the Co-ordinator, GPAT, on or before March 15th , 2010, along with Demand Draft of Rs. 400/- as fee for change of Examination City.

NOTE: Incomplete or defective applications will be rejected outright.

4.2. Instructions for filling Application Form and Acknowledgement Card

4.2.1. General

a) The instructions given below for filling the Application Form must be followed meticulously. Refer to the Sample Application Form at the end of this section.

b) For Items 1, 6, 7, 8 10, 11, 12, 14, 15, 16, 17, 18, 19, 20, the candidate must write the required information in ink with black ball point pen in the boxes provided and then darken the appropriate bubble(s), using dark HB pencil only. In case of any discrepancy in the marked bubble and the corresponding boxes, the information provided through the bubble(s) will be taken as final. The text boxes are provided only for guidance.

c) For Items 1 to 13, the candidate must provide information by filling the appropriate bubble(s) using dark HB pencil only.

d) Darken the appropriate bubble(s) by filling it completely. For correcting any entry, completely erase the previous mark using a soft eraser and remove all smudges before re-filling.

e) Only BLACK BALL POINT PEN must be used for filling Items 14 to 20.

4.2.2. Itemwise Instructions for filling Application Form

Item 1: Name of the Candidate as in 10th Class Certificate

Fill in your name in CAPITAL LETTERS as recorded in the High School (Class 10th) certificate by your Board/ University/Institute and darken the appropriate bubbles. Your name in the GPAT scorecard will appear exactly as filled in the Application Form. In case of any change in the name/surname at any stage has to be duly supported by a proper affidavit.

NOTE: In case, your name has more than 30 characters (including blanks), abbreviate it suitably to accommodate within the space provided. For example, the name RAMAKRISNA VELLURAO VENKATESH KUMAR AYYAR can be abbreviated as,

R

A

M

A

K

R

I

S

N

A

V

V

E

N

K

A

T

E

S

H

K

A

Y

Y

A

R

Item 2: Nationality

Darken the appropriate bubble:

INDIAN or FOREIGNER

Item 3: Gender

Darken the appropriate bubble, MALE or FEMALE.

Item 4: Category

Darken the appropriate bubble:

SC : Scheduled Caste, ST: Scheduled Tribe, OBC: Other Backward Class (non creamy layer), GN: All others

NOTE: Candidate claiming concession for buying Application Form under SC and ST categories must attach a recently obtained and duly attested copy of Caste Certificate, issued by a competent authority (see section 4.3). If the Caste Certificate is found improper, the application will be rejected

Item 5: Person with Disability (PD)

Darken the appropriate bubble YES or NO

NOTE: PD candidate claiming concession for buying Application Form must attach an attested copy of Disability Certificate issued by appropriate medical authority. Applications with improper Disability Certificate will be rejected. If any PD candidate requires the services of an Amanuensis, he/she must attach a request for this with the Application Form.

Item 6: Date of Birth

Fill in your date of birth as given in your High School (Class 10th) certificate in the space provided and darken the appropriate bubbles.

Example: If the date of birth is 16th September 1988, fill in as,

Date

Month

Year

1

6

0

9

8

8

Item 7: Choice of Examination Cities

Fill in your choice of two Examination Cities in order of preference as 1st choice and 2nd choice, and darken the appropriate bubbles.

Refer to Annexure II-A, which lists the cities where GPAT 2010 will be conducted and the corresponding three digit CODES.

Item 8: Year of Degree

Fill in the Year of passing / appearing in the qualifying degree examination and darken the appropriate bubbles.

Item 9: Photograph

Paste your recent passport size clear front facial high contrast colour photograph (Size: 3 cm width x 4 cm height) in the box provided. Ensure that the application number is written at the back side of the photograph before it is pasted within the box. Please use good quality adhesive/glue, so that it does not get detached from the Application Form. The photograph should not be stapled. The photograph will be scanned and the scanned image will appear on the admit card as well as the scorecard. The photograph should NOT be attested or signed by anyone.

Item 10: Address for Correspondence

Write your postal address in CAPITAL LETTERS within the box using only black ball point pen. The address should be legible and should include the NAME of the candidate, PINCODE and E mail.

NOTE: Scanned copy of this address will be used directly in all correspondence including mailing of ADMIT CARD and SCORECARD.

Item 11: Full Signature of the Candidate

Sign in full within the box provided, using only black ball point pen. The form must be signed only by the candidate and not by any other person. Signature in the form of initials is not permitted. This signature will be scanned and put on the Admit Card as well as the Scorecard.

NOTE: If the candidate’s signature on the Optical Response Sheet (ORS), at the time of the examination, does not match with the signature on the Admit Card, the candidate will be disqualified.

Item 12: Name of Parent/Guardian

Fill in the name of your mother, father/guardian in CAPITAL LETTERS in the space provided and darken the appropriate bubbles.

Item 13: Relationship of Parent/Guardian to the candidate

Darken the appropriate bubble father/mother/guardian

Item 14: Bank/GPAT Office Pay-in-slip number

Fill in the bank/GPAT Office Pay-in-slip number and darken the appropriate bubbles.

Item 15: Details of the Demand Draft enclosed

Fill in the Demand Draft number, date of Demand Draft and darken the appropriate bubbles.

Item 16: Landline Phone with STD Code

Fill in landline number with the STD code including the leading 0, at which you can be contacted. Darken the appropriate bubbles.

Item 17: Mobile Phone with Code

Fill in mobile phone number including the leading 0, at which you can be contacted. Darken the appropriate bubbles.

Item 18: Declaration by the Candidate

Read and sign the declaration using only black ball point pen, and write the Place and Date. The signature must be identical to that in Item 11.

Item 19: Check List

Fill up items in the Check List by ticking in the appropriate boxes.

Item 20: List of Enclosures

Tick YES for the attachments enclosed with the Application Form, otherwise, tick NO.

4.2.3. Filling of Acknowledgement Card

Fill in the Acknowledgement Card with all the required details and enclose it with the Application Form.

4.3. Authorities empowered to issue Certificates

4.3.1. SC/ST Category

a) District Magistrate/ Additional District Magistrate/ Collector/ Deputy Collector/ Deputy Commissioner/ Additional Deputy Commissioner/ 1st Class Stipendiary Magistrate/ City Magistrate/ Sub-Divisional Magistrate/ Taluk Magistrate/ Executive Magistrate/ Extra Assistant Commissioner

b) Chief Presidency Magistrate/ Additional Chief Presidency Magistrate/ Presidency Magistrate

c) Revenue Officer not below the rank of Tashildar

d) Sub-Divisional Officer of the area where the Candidate and/or her/his family normally resides

e) Administrator/ Secretary to Administrator/ Development Officer (Lakshadweep Islands) Certificate issued by any other official will not be accepted.

4.3.2. PD Category

In order to avail concession under PD category, the candidates should ensure themselves that they have attached recently obtained proper PD certificate, which shall be required to be submitted to the admitting institution at the time of admission. The onus of verifying PD certificate lies with the admitting institute. The GPAT committee will not be responsible for any incorrect declaration of his/her PD status.

4.3.3. OBC (non creamy layer)

In order to avail concession under OBC (non creamy layer) category, the candidates should ensure themselves that they have obtained proper OBC (non creamy layer) certificate, which shall be required to be submitted to the admitting institution at the time of admission. The onus of verifying OBC (non creamy layer) certificate lies with the admitting institute. The GPAT committee will not be responsible for any incorrect declaration of his/her category.

4.4. Filling and Submission of Application Envelope

On the application envelope, fill in the CODE of the examination city corresponding to your first choice (Item No. 7 of Application Form).

Write your postal address in the designated space. The envelope should be addressed to the Co-ordinator, GPAT corresponding to the 1st Choice of Examination City of the candidate.

Completed Application Form must reach the Co-ordinator, GPAT before Monday, 1st March 2010, by Registered/Speed Post only. It may also be submitted in person at the GPAT office counter.

APPLICATION FORM – PHARMA-GAT 2010

Before filling up this form read the instruction in the Information Brochure

· USE HB PENCIL ONLY TO DARKEN THE BUBBLES

· DO NOT MAKE ANY STRAY MARKS ON THIS SHEET

· DARKEN THE BUBBLES FULLY

· ERASE COMPLETELY BEFORE MAKING CORRECTIONS

APPLICATION FORM INCOMPLETE IN ANY RESPECT WILL BE REJECTED

1. Name of the Candidate as in 10th class certificate (in capital letters)

2. Nationality

3. Gender

4. Category

5. Person with Disability

6. Date of birth

7. Choice of Examination Cities

8. Year of Degree

9. Photograph

10. Address for Correspondence

(Write with BLACK BALL POINT PEN in Capital Letters)

Name:

Address:

PIN CODE:

11. Full signature of the Candidate (with BLACK BALL POINT PEN only)

12. Name of Parent/Guardian (in capital letters)

13. Relationship of Parent/Guardian to the Candidate

14. Bank/GPAT Office Pay-in-slip number

15. Details of Demand Draft enclosed

16. Landline Phone with STD Code

17. Mobile Phone with Code

18. Declaration by the Candidate

I hereby declare that all the particulars stated in this application are true to the best of my knowledge and belief. I have read the Information Brochure and I shall abide the terms and conditions therein. In the event of suppression or distortion of any fact in my application form, I understand that I will be denied the opportunity to appear in PHARMA-GAT 2010. Further, if any such suppression or distortion of facts is found after appearing in the examination, any admission/degree acquired on the basis of PHARMA-GAT 2010 score is liable to be cancelled.

Place: Signature of the Candidate

Date:

19. Checklist

Yes No

a. Filled in all the items 1-18 completely?

b. Written (with black ball point pen) the address for correspondence under item 10?

c. Pasted a recent photograph in the box under item 9?

d. Signed (with black ball point pen) in the box under item 11?

e. Signed (with black ball point pen) in the box under item 18?

f. Fill in the code of first choice of examination city on application envelope?

g. Kept a photocopy of the filled application form for your own records?

20. List of enclosures

Yes No N/A

a. Original Bank Pay-in Slip / Receipt from GPAT office

b. Attested copy of SC/ST Certificate (if applicable)

c. Attested copy of PD Certificate (if applicable)

d. In case of PD candidate, requested for Amanuensis (if applicable)

e. Attested copy of the affidavit for Change of Name/Surname (if applicable)

f. Duly completed and stamped Acknowledgement Card

ANNEXURE – I: Syllabi for GPAT Paper

Natural Products: Pharmacognosy & Phytochemistry � Chemistry, tests, isolation, characterization and estimation of phytopharmaceuticals belonging to the group of Alkaloids, Glycosides, Terpenoids, Steroids, Bioflavanoids, Purines, Guggul lipids. Pharmacognosy of crude drugs that contain the above constituents. Standardization of raw materials and herbal products. WHO guidelines. Quantitative microscopy including modern techniques used for evaluation. Biotechnological principles and techniques for plant development, Tissue culture.

Pharmacology: General pharmacological principles including Toxicology. Drug interaction. Pharmacology of drugs acting on Central nervous system, Cardiovascular system, Autonomic nervous system, Gastro intestinal system and Respiratory system. Pharmacology of Autocoids, Hormones, Hormone antagonists, chemotherapeutic agents including anticancer drugs. Bioassays, Immuno Pharmacology. Drugs acting on the blood & blood forming organs. Drugs acting on the renal system.

Medicinal Chemistry: Structure, nomenclature, classification, synthesis, SAR and metabolism of the following category of drugs, which are official in Indian Pharmacopoeia and British Pharmacopoeia. Introduction to drug design. Stereochemistry of drug molecules. Hypnotics and Sedatives, Analgesics, NSAIDS, Neuroleptics, Antidepressants, Anxiolytics, Anticonvulsants, Antihistaminics, Local Anaesthetics, Cardio Vascular drugs � Antianginal agents Vasodilators, Adrenergic & Cholinergic drugs, Cardiotonic agents, Diuretics, Antijypertensive drugs, Hypoglycemic agents, Antilipedmic agents, Coagulants, Anticoagulants, Antiplatelet agents. Chemotherapeutic agents � Antibiotics, Antibacterials, Sulphadrugs. Antiproliozoal drugs, Antiviral, Antitubercular, Antimalarial, Anticancer, Antiamoebic drugs. Diagnostic agents. Preparation and storage and uses of official Radiopharmaceuticals, Vitamins and Hormones. Eicosonoids and their application.

Pharmaceutics : Development, manufacturing standards Q.C. limits, labeling, as per the pharmacopoeal requirements. Storage of different dosage forms and new drug delivery systems. Biopharmaceutics and Pharmacokinetics and their importance in formulation. Formulation and preparation of cosmetics � lipstick, shampoo, creams, nail preparations and dentifrices. Pharmaceutical calculations.

Pharmaceutical Jurisprudence: Drugs and cosmetics Act and rules with respect to manufacture, sales and storage. Pharmacy Act. Pharmaceutical ethics.

Pharmaceutical Analysis: Principles, instrumentation and applications of the following: Absorption spectroscopy (UV, visible & IR). Fluorimetry, Flame photometry, Potentiometry. Conductometry and Plarography. Pharmacopoeial assays. Principles of NMR, ESR, Mass spectroscopy. X-ray diffraction analysis and different chromatographic methods.

Biochemistry. Biochemical role of hormones, Vitamins, Enzymes, Nucleic acids, Bioenergetics. General principles of immunology. Immunological. Metabolism of carbohydrate, lipids, proteins. Methods to determine, kidney & liver function. Lipid profiles.

Microbiology : Principles and methods of microbio0logical assays of the Pharmacopoeia. Methods of preparation of official sera and vaccines. Serological and diagnostics tests. Applications of microorganisms in Bio Conversions and in Pharmaceutical industry.

Clinical Pharmacy : Therapeutic Drug Monitoring Dosage regimen in Pregnancy and Lactation, Pediatrics and Geriatrics. Renal and hepatic impairment. Drug � Drug interactions and Drug � food interactions, Adverse Drug reactions. Medication History, interview and Patient counseling.

Patents, Profits & Power

noreply@blogger.com (◄◄▌┼ÅŚ╠╣uтσŚ╠╣ รٱภg╠╣┼▐►►) — Fri, 08 Jan 2010 06:57:00 +0000

Patents, Profits & Power
Publisher: Kogan Page | ISBN: 0749436417 | edition 2002-07-15 | PDF | 256 pages | 5,53 mb

Highlights the hazards facing intellectual property protection in the information age.* IBM estimates profits from licensing technologies in 2000 were $1.5 billion.* US pharma industries estimate losses of $500 million a year due to poor patent protection.* International in its scope, includes international enforcement mechanisms* Uses case studies and examples to support the text.The value of today's businesses is in the collective knowledge and innovation of their employees and leaders. Consequently, intellectual property (IP) protection has become the focus of considerable legal and regulatory attention, at both national and international levels. This exploration of the rapid development of IP in the global economy reveals theft, piracy and infringements of IP rights at every level, from the state to the individual. Curtis Cook examines the less desirable players on the world stage, why they choose to defy the law, how the rest of the world is responding, and how you can survive and thrive in this environment.On the way he looks at the way that intellectual property rights have rapidly expanded in the last 100 years, how intellectual assets have become the new wealth, how global IP enforcers are losing the battle to protect intellectual property against rogue nations, why intellectual property at cyberspeed is a different game, and how the intellectual property regime is being undermined.Fully international in its scope and subject matter, "Patents, Profits and Power" highlights the hazards facing intellectual property protection in the information age. Packed with international case studies and examples, this unique title will prove an invaluable source for anyone who creates forprofit... or power.
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Big Pharma

noreply@blogger.com (◄◄▌┼ÅŚ╠╣uтσŚ╠╣ รٱภg╠╣┼▐►►) — Fri, 08 Jan 2010 06:55:00 +0000

Big Pharma: Exposing the Global Healthcare Agenda

Jacky Law | Basic Books | 256 PGs | 2006-02-26 | ISBN : 0786717831 | PDF | 1.8 MB

Last year the pharmaceutical industry had sales in excess of $300 billion. Clearly one way or another we all pay — whether we buy the drugs directly or through taxation. But is it less clear that we are getting value for money?

In one of the first independent investigations of the modern healthcare system, Jacky Law shows how a small number of corporations have come to dominate the healthcare agenda in Britain and America. She reveals a system in which the relentless pursuit of profit is crowding out the public good. Effective regulators are under intense pressure from corporate lobbies, and companies spend more money on marketing than they spend on research and development. Meanwhile the cost of new drugs rises relentlessly while the number of original new products declines.
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Healthcare Investing

noreply@blogger.com (◄◄▌┼ÅŚ╠╣uтσŚ╠╣ รٱภg╠╣┼▐►►) — Fri, 08 Jan 2010 06:43:00 +0000

Healthcare Investing: Profiting from the New World of Pharma, Biotech, and Health Care Services

Publisher: McGraw-Hill | ISBN: 0071597484 | edition 2008 | PDF | 304 pages | 1,73 mb

Health-Care Investing provides a thorough explanation of how the industry's mammoth size and complexity can be worked to your advantage and why health care is more resistant to changes in economic cycles than other markets.
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Oxford Dictionary of Biochemistry and Molecular Biology Second Edition

noreply@blogger.com (◄◄▌┼ÅŚ╠╣uтσŚ╠╣ รٱภg╠╣┼▐►►) — Tue, 30 Jun 2009 11:23:00 +0000

Oxford Dictionary of Biochemistry and Molecular Biology Second Edition
Oxford University Press, USA | ISBN:0198529171 | 2006-08-24 | PDF | 736 pages | 5.7 MB

The Oxford Dictionary of Biochemistry and Molecular Biology provides a comprehensive survey of current biochemistry and molecular biology. Over the last few years, the language of Biochemistry and Molecular Biology has expanded enormously to the extent that few scientists can expect to be familiar with all aspects of it. This is partly due to the Genome projects and the successive -omics projects which have provided comprehensive information about genes, the functions of gene products, and cellular processes. At the same time, terms from other subject areas appear increasingly in the biochemical literature. The popular Dictionary has been comprehensively reviewed and updated to include many important new concepts and words. The entries are short but informative, providing up-to-date information on a broad range of topics, including definitions for selected terms from Bioinformatics, Biophysics, Cell Biology, Chemistry, Genetics, Immunology, Mathematics, Microbiology, Pharmacology, Systems Biology, and Toxicology. There are over 21,000 main entries, which give details of biochemical substances and the processes in which they are involved, define methods and concepts in molecular biology, and give definitions of biochemical symbols and abbreviations. It points out pitfalls where terms are often confused. It explains the precise syntax of biochemical terms, such as Greek letters and other formatting, which are lost when searching the Internet. In addition the dictionary is illustrated with over 900 chemical structures.

The Oxford Dictionary of Biochemistry and Molecular Biology will serve as an invaluable reference for biochemists and molecular biologists seeking information outside their own fields, and for those wishing to revisit fundamental principles.

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G Protein-coupled Receptors

noreply@blogger.com (◄◄▌┼ÅŚ╠╣uтσŚ╠╣ รٱภg╠╣┼▐►►) — Tue, 30 Jun 2009 11:18:00 +0000

G Protein-coupled Receptors: Molecular Pharmacology By Georges Vauquelin, Bengt von Mentzer

Publisher: Wiley | 28-01-2008 | ISBN: 047051647X | 264 pages | 73.9 Mb

G protein-coupled receptors (GPCRs) are membrane proteins that transduce a vast array of extracellular signals into intracellular reactions ranging from cell-cell communication processes to physiological responses. They play an important role in a variety of diseases from cancer and diabetes, to neurodegenerative, inflammatory and respiratory disorders. GPCRs are therefore of utmost interest in drug development: over half of all prescription drugs currently on the market act by targeting these receptors directly or indirectly.

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Bioequivalence and Statistics in Clinical Pharmacology

noreply@blogger.com (◄◄▌┼ÅŚ╠╣uтσŚ╠╣ รٱภg╠╣┼▐►►) — Tue, 30 Jun 2009 11:12:00 +0000

Bioequivalence and Statistics in Clinical Pharmacology By Scott Patterson, Byron Jones

Publisher: Chapman & Hall/CRC | 10-11-2005 | ISBN: 1584885300 | 400 pages | 2.26 Mb

Establishing techniques used in the assessment of bioequivalence, this work describes the use of statistics in clinical pharmacology studies of safety, ECG monitoring, efficacy, and population pharmacokinetics. The authors demonstrate study design, analysis, and interpretation of data using real-data examples from bioequivalence and clinical pharmacology studies. They feature a wide range of datasets, as well as SAS and SPLUS code (available for download) and examine regulatory considerations regarding the application of statistics in drug development. This work, as stated in a recent issue of Biometrics, "provides a springboard for all scientists from academia who are looking to do research in this area of medical applications."
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Pharmacy Case Studies

noreply@blogger.com (◄◄▌┼ÅŚ╠╣uтσŚ╠╣ รٱภg╠╣┼▐►►) — Tue, 30 Jun 2009 11:01:00 +0000

Soraya Dhillon, Rebekah Raymond "Pharmacy Case Studies"
Pharmaceutical Press | 2009-02-28 | ISBN: 0853697248 | Pages: 458 | PDF | 1.49 MB

Whilst most pharmacy undergraduate texts are subject specific, "Pharmacy Case Studies" encourages students to take an integral approach to pharmacy via a series of pharmacy cases. Knowledge gained within the individual areas of law and ethics, pharmaceutics, pharmacology and pathology are tested by each example, bringing together all areas taught on the degree course. Each chapter contains five case studies, starting with uncomplicated cases and increasing in complexity as they expand.

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Pharmacology eBook Collections: Drugs - The Straight Facts

noreply@blogger.com (◄◄▌┼ÅŚ╠╣uтσŚ╠╣ รٱภg╠╣┼▐►►) — Tue, 30 Jun 2009 10:53:00 +0000

Drugs: The Straight Facts provides straightforward information on the history and use of crucial, lifesaving medications as well as the world’s most widely abused substances, along with easy-to-understand explanations of how these substances can harm or heal the mind and body of the user. Original News

Therapeutic Prescription Medications

Alzheimer's Disease and Memory Drugs | C. Borda | 2006 | ISBN: 0791085554 | 97 pp | 2.4 Mb | C$34.66
Anti-Anxiety Drugs | D. Toufexis, S.E. Hammack | 2006 | ISBN: 0791085562 | 125 pp | 2.3 Mb | C$34.66
Antidepressants | E.S. Mitchell | 2004 | ISBN: 0791076350 | 125 pp | 10.7 Mb | C$34.66
Birth Control Pills | J. Zonderman, L. Shader | 2006 | ISBN: 0791085538 | 96 pp | 2.4 Mb | C$34.66
Cancer Drugs | J. Matry-Devoti | 2007 | ISBN: 0791085546 | 137 pp | 4.1 Mb | C$34.66
Codeine | B.M. Kane | 2006 | ISBN: 0791085503 | 101 pp | 3.0 Mb | C$34.66
HIV/AIDS Treatment Drugs | B.M. Kane | 2008 | ISBN: 079108552X | 121 pp | 2.6 Mb | C$34.66
Prescription Pain Relievers | M. Foster Olive | 2005 | ISBN: 0791083756 | 113 pp | 10.4 Mb | C$34.66
Ritalin and Other Methylphenidate-Containing Drugs | C. Ferreiro | 2004 | ISBN: 0791076377 | 107 pp | 6.5 Mb | C$34.66
Sleep Aids | M. Foster Olive | 2005 | ISBN: 0791082008 | 107 pp | 6.9 Mb | C$34.66

Illicit Drugs of Abuse

Barbiturates | D. Henn, D. DeEugenio | 2007 | ISBN: 0791085481 | 102 pp | 3.6 Mb | C$34.66
Cocaine | H. Lehr Wagner | 2003 | ISBN: 0791072606 | 101 pp | 11.3 Mb | C$34.66
Date Rape Drugs | G.B. Kehner | 2004 | ISBN: 0791076342 | 95 pp | 6.1 Mb | C$34.66
Designer Drugs | M. Foster Olive | 2004 | ISBN: 0791076385 | 97 pp | 6.5 Mb | C$34.66
Ecstasy | B.E. Schroeder | 2003 | ISBN: 0791076334 | 97 pp | 6.4 Mb | C$34.66
Hallucinogens | R. Mehling | 2003 | ISBN: 0791072614 | 126 pp | 11.9 Mb | C$34.66
Heroin | C. Ferreiro | 2003 | ISBN: 0791072622 | 105 pp | 12.0 Mb | C$34.66
Inhalants | I.A. Lobo | 2004 | ISBN: 0791076369 | 105 pp | 9.2 Mb | C$34.66
LSD | M. Foster Olive | 2008 | ISBN: 0791097099 | 104 pp | 2.5 Mb | C$34.66
Marijuana | R. Mehling | 2003 | ISBN: 0791072630 | 105 pp | 9.7 Mb | C$34.66
Morphine | G.D. Busse | 2006 | ISBN: 0791085511 | 103 pp | 3.0 Mb | C$34.66
Opium | T.M. Santella | 2006 | ISBN: 0791085473 | 120 pp | 7.2 Mb | C$34.66
Peyote And Mescaline | M. Foster Olive | 2007 | ISBN: 0791085457 | 94 pp | 5.6 Mb | C$34.66
Quaaludes | G.T. Gass | 2008 | ISBN: 0791085465 | 97 pp | 1.9 Mb | C$34.66

Drugs of Potential Abuse

Alcohol | H. Lehr Wagner | 2003 | ISBN: 0791072592 | 104 pp | 14.0 Mb | C$34.66
Body enhancement Products | T.M. Santella | 2004 | ISBN: 0791081974 | 121 pp | 10.6 Mb | C$34.66
Diet Pills | D. Henn, D. DeEugenio | 2004 | ISBN: 0791081982 | 121 pp | 6.5 Mb | C$34.66
Nicotine | H. Lehr Wagner | 2003 | ISBN: 0791072649 | 102 pp | 10.9 Mb | C$34.66

Therapeutic Prescription Medications: Rapidshare Download (45 Mb)

Illicit Drugs of Abuse: Rapidshare Download (86 Mb)

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Advanced Pharmaceutics: Physicochemical Principles

noreply@blogger.com (◄◄▌┼ÅŚ╠╣uтσŚ╠╣ รٱภg╠╣┼▐►►) — Tue, 07 Apr 2009 18:29:00 +0000

Advanced Pharmaceutics: Physicochemical Principles
by Cherng-ju Kim

ISBN: 0203492919 | year 2004 | English
512pages | pdf | size: 7,38 Mb

Features:
• Explores the mathematical foundation that underpins the concepts
• Contains numerous graphs and extensive, worked-out explanations of equations
• Discusses the latest advances in the use of polymers in dosage forms
• Includes a detailed review and analysis of dosage form design criteria
Discussing comprehensive range of topics, Advanced Pharmaceutics reviews all aspects of physical pharmacy. The book explains the basic, mechanistic, and quantitative interpretation skills needed to solve physical pharmacy related problems. The author supplies a strong fundamental background and extensively covers thermodynamics, ionic equilibria, solutions and distribution, surface chemistry and colloids, kinetics, diffusion, and polymer science. He outlines the latest research on diffusion through a membrane and the use of polymers in dosage forms.
Packed with formulae and models, the book demonstrates the development of each and then describes the use of those models for a variety of formulation situations. The author's detailed explanation of the evolution of the formulae provides a clear understanding of when and how they are used. This bottom-up approach delineates the evolution of the formulae and gives a clear understanding of when and how they should be used.
Advanced Pharmaceutics provides an in-depth review and analysis of dosage form design criteria that you can rapidly implement in your day-to-day work.
Contents
1. Thermodynamics
2. Ionic Equilibrium
3. Solutions and Distribution
4. Surface Chemistry and Colloids
5. Diffusion
6. Polymer Science

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Quality Assurance in the Analytical Chemistry Laboratory

noreply@blogger.com (◄◄▌┼ÅŚ╠╣uтσŚ╠╣ รٱภg╠╣┼▐►►) — Tue, 07 Apr 2009 18:15:00 +0000

Analytical chemical results touch everyones lives can we eat the food? do I have a disease? did the defendant leave his DNA at the crime scene? should I invest in that gold mine? When a chemist measures something how do we know that the result is appropriate? What is fit for purpose in the context of analytical chemistry? Many manufacturing and service companies have embraced traditional statistical approaches to quality assurance, and these have been adopted by analytical chemistry laboratories. However the right chemical answer is never known, so there is not a direct parallel with the manufacture of ball bearings which can be measured and assessed. The customer of the analytical services relies on the quality assurance and quality control procedures adopted by the laboratory. It is the totality of the QA effort, perhaps first brought together in this text, that gives the customer confidence in the result. QA in the Analytical Chemistry Laboratory takes the reader through all aspects of QA, from the statistical basics and quality control tools to becoming accredited to international standards. The latest understanding of concepts such as measurement uncertainty and metrological traceability are explained for a working chemist or her client. How to design experiments to optimize an analytical process is included, together with the necessary statistics to analyze the results.

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Analytical Chemistry for Technicians

noreply@blogger.com (◄◄▌┼ÅŚ╠╣uтσŚ╠╣ รٱภg╠╣┼▐►►) — Tue, 07 Apr 2009 18:09:00 +0000

Like its bestselling predecessors, this thoroughly updated third edition is a powerful training tool for entry-level chemistry technicians. It explains analytical chemistry and instrumental analysis principles and how to apply them in the real world. It includes over 50 workplace scene side boxes that illustrate techniques; a CD that enhances training activities; and a working LIMS system that can be used in training programs. It provides over sixty experiments specifically relevant to the laboratory technician and each chapter contains a Questions and Problems section. The author uses the Voluntary Industry Standards for chemical process industry technicians.

." . . this book can be a valuable resource for any chemistry student and indeed, for practitioners, laboratory scientists, teachers, and professors-anyone who needs to know something about how laboratory analyses are carried out...Numerous experiments and questions at the end of the chapter illustrate concepts and manipulations taught in that chapter. The accompanying CD-ROM illustrates many of the concepts presented in the book and is designed to reinforce what has been learned. Summing up: Highly Recommended" -J.A. Siegel, Michigan State University "[The book has] comprehensive coverage of the analytical techniques students will most likely encounter when entering an industrial position. [Charts] provide a quick and useful summary of key ideas." - Journal of Chemical Education, Vol. 82, No. 1, January 2005

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modern pharmaceutics

noreply@blogger.com (◄◄▌┼ÅŚ╠╣uтσŚ╠╣ รٱภg╠╣┼▐►►) — Wed, 01 Apr 2009 11:43:00 +0000

Completely revised and expanded throughout. Presents a comprehensive integrated, sequenced approach to drug dosage formulation, design, and evaluation. Indentifies the pharmacodynamic and physicochemical factors influencing drug action through various routes of administration.

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Mechanisms in Organic Reactions

noreply@blogger.com (◄◄▌┼ÅŚ╠╣uтσŚ╠╣ รٱภg╠╣┼▐►►) — Thu, 26 Mar 2009 12:12:00 +0000

SDigital mechanism in Organic Reactions By Richard A. Jackson
Publisher: Royal Society of Chemistry | ISBN: 0854046429 | 2000 | PDF | 199 pages | 19 Mb
This work helps students identify basic reaction types in organic chemistry and methods for determining mechanisms, including product studies, kinetics and the identification of intermediates.

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March's Advanced Organic Chemistry: Reactions, Mechanisms, and Structure, 6th Edition»

noreply@blogger.com (◄◄▌┼ÅŚ╠╣uтσŚ╠╣ รٱภg╠╣┼▐►►) — Thu, 26 Mar 2009 12:10:00 +0000

The Sixth Edition of a classic in organic chemistry continues its tradition of excellence Now in its sixth edition, March's Advanced Organic Chemistry remains the gold standard in organic chemistry. Throughout its six editions, students and chemists from around the world have relied on it as an essential resource for planning and executing synthetic reactions.

The Sixth Edition brings the text completely current with the most recent organic reactions. In addition, the references have been updated to enable readers to find the latest primary and review literature with ease.

New features include:

More than 25,000 references to the literature to facilitate further research
Revised mechanisms, where required, that explain concepts in clear modern terms
Revisions and updates to each chapter to bring them all fully up to date with the latest reactions and discoveries
A revised Appendix B to facilitate correlating chapter sections with synthetic transformations

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A Guidebook to Mechanism in Organic Chemistry (6th Edition)

noreply@blogger.com (◄◄▌┼ÅŚ╠╣uтσŚ╠╣ รٱภg╠╣┼▐►►) — Thu, 26 Mar 2009 12:02:00 +0000

Peter Sykes, "A Guidebook to mechansm in Organic Chemistry (6th edition)"
Prentice Hall | 1996-02-19 | ISBN: 0582446953 | 432 pages | PDF | 4,7 MB

A classic textbook on mechanistic organic chemistry is characterised particularly by its clarity, careful choice of examples and its general approach that is designed to lead to a ready understanding of the subject matter. This guidebook is aimed clearly at the needs of the student, with a thorough understanding of, and provision for, the potential conceptual difficulties he or she is likely to encounter.

Enjoy this great book! Brought to you by ashutosh singh parmar

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Vogel's Textbook of Practical Organic Chemistry (5th Edition)

noreply@blogger.com (◄◄▌┼ÅŚ╠╣uтσŚ╠╣ รٱภg╠╣┼▐►►) — Thu, 26 Mar 2009 11:58:00 +0000

Vogel's Textbook of Practical Organic Chemistry

It has the most trustworthy procedures for the synthesis of organic compounds with the underlying philosophy behind the reactions complete with the mechanism. Even briefly described procedures are easy to follow. An example in point is the Swern's oxidation. It also includes characterization of compounds using both chemical and spectroscopic methods thus covering the whole spectrum of practical organic chemistry. Almost all the other information to be required by an organic synthetic chemist in the laboratory is also included. I do not know of any other single book that can rival the Vogel. I, however, would very much like to see a moderately priced new edition.

Vogel also discusses aliphatic, heterocyclic, and aromatic compounds and introduces spectroscopic methods. Vogel is recommended for advanced lab course that requires frequent modification of lab procedures and reference for chemists

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Medicinal Chemistry of Bioactive Natural Products

noreply@blogger.com (◄◄▌┼ÅŚ╠╣uтσŚ╠╣ รٱภg╠╣┼▐►►) — Thu, 26 Mar 2009 11:52:00 +0000

Current discoveries and research into bioactive natural products Medicinal Chemistry of Bioactive Natural Products provides a much-needed survey of bioactive natural products and their applications in medicinal chemistry. This comprehensive reference features articles by some of the world's leading scientists in the field on discovery, structure elucidation, and elegant synthetic strategies--developed for natural products--with an emphasis on the structure activity relationship of bioactive natural products. The topics have been carefully chosen on the basis of relevance to current research and to importance as clinicially useful agents.

Rather than attempting to be a comprehensive encyclopedia of bioactive natural products, Medicinal Chemistry of Bioactive Natural Products guides the reader to the key developments in the field. By providing not only practical detail but a historical perspective on the chemistry and biology of the compounds under consideration, the book serves as a handy resource for researchers in their own work developing pharmaceuticals, and as an inspiring introduction for young scientists to the dynamic field of bioactive natural products research.

Enhanced by examples with updated research results, the discussion covers such topics as:
* The chemistry and biology of epothilones
* Vancomycin and other glycopeptide antibiotic derivates
* Antitumor and other related activities of Taxol and its analogs
* The antimalarial properties of the traditional Chinese medicine, Quinghaosu (artemisinin)
* Huperzine A: A natural drug for the treatment of Alzheimer's disease
* The medicinal chemistry of ginkgolides from Ginkgo biloba
* Recent progress in Calophyllum coumarins as potent anti-HIV agents
* Plant-derived anti-HIV agents and analogs
* Chemical synthesis of annonaceous acetogenins and their structurally modified mimics

1 The Chemistry and Biology of Epothilones—Lead Structures for the Discovery of Improved Microtubule Inhibitors (Karl-Heinz Altmann).
2 The Chemistry and Biology of Vancomycin and Other Glycopeptide Antibiotic Derivatives (Roderich D. Su¨ssmuth).
3 Structure Modifications and Their Influences on Antitumor and Other Related Activities of Taxol and Its Analogs (Wei-Shuo Fang, Qi-Cheng Fang, and Xiao-Tian Liang).
4 The Overview of Studies on Huperzine A: A Natural Drug for the Treatment of Alzheimer’s Disease (Da-Yuan Zhu, Chang-Heng Tan, and Yi-Ming Li).
5 Qinghaosu (Artemisinin)—A Fantastic Antimalarial Drug from a Traditional Chinese Medicine (Ying Li, Hao Huang, and Yu-Lin Wu).
6 Progress of Studies on the Natural Cembranoids from the Soft Coral Species of Sarcophyton Genus (Yulin Li, Lizeng Peng, and Tao Zhang).
7 Medicinal Chemistry of Ginkgolides from Ginkgo biloba (Kristian Strømgaard).
8 Recent Progress in Calophyllum Coumarins as Potent Anti-HIV Agents (Lin Wang, Tao Ma, and Gang Liu).
9 Recent Progress and Prospects on Plant-Derived Anti-HIV Agents and Analogs (Donglei Yu and Kuo-Hsiung Lee).
10 Recent Progress on the Chemical Synthesis of Annonaceous Acetogenins and Their Structurally Modified Mimics (Tai-Shan Hu, Yu-Lin Wu, and Zhu-Jun Yao).

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drug synthesis

noreply@blogger.com (◄◄▌┼ÅŚ╠╣uтσŚ╠╣ รٱภg╠╣┼▐►►) — Thu, 26 Mar 2009 11:45:00 +0000

Contemporary Drug Synthesis by: Jie Jack Li Douglas
Publisher: Wiley-Interscience | ISBN: 0471214809 | 2004-06-25 | Pages: 240 | PDF | 2.7 MB

An integrated and insightful look at successful drug synthesis in today’s drug discovery market
The pharmaceutical industry is unquestionably vibrant today, with drug synthesis making a vital contribution. Whether in the early developmental stages of identifying and optimizing a lead, or the latter stages of process development and cost-effective scale-up, the ability to design elegant and economical synthetic routes is often a major factor in the eventual viability and commercial success of a drug.

Contemporary Drug Synthesis examines how leading researchers and manufacturers have integrated chemistry, biology, pharmacokinetics, and a host of other disciplines in the creation and development of leading drugs. Authored by four of the pharmaceutical industry’s most respected scientists, this timely volume:

* Focuses on the processes that resulted in high-profile drugs including Lipitor, Celebrex, Viagra, Gleevec, Nexium, Claritin, and over a dozen others
* Provides an in-depth introduction to each drug, followed by a detailed account of its synthesis
* Organizes the drugs into fourteen therapeutic areas for clarity and ease of use

Process chemists provide an essential bridge between chemistry and the marketplace, creating scientifically practical drug processes while never losing sight of the commercial viability of those processes. Contemporary Drug Synthesis meets the needs of a growing community of researchers in pharmaceutical research and development, and is both a useful guide for practicing pharmaceutical scientists and an excellent text for medicinal and organic chemistry
students.

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