patentstorm.us

CONSTITUTIVE PROMOTERS FROM POPLAR AND USES THEREOF

Application Number: 20130133113
Publication Date: 2013-05-23
Inventor: Alellyx S.A.,

The present invention relates to nucleic acid molecules corresponding to regulatory portions of genes whose expression is constitutive. The invention also relates to compositions and methods of using the same to regulate the expression, in a constitutive manner, of genes and/or any kind of nucleotide sequences in a plant. Nucleic acid molecules and its compositions include novel nucleotide sequences for constitutive promoter identified in and isolated from poplar (Populus spp). Methods ...

METHOD OF PLANT GENOME DESIGN, METHOD OF CREATING NEW CULTIVAR AND NEW CULTIVAR

Application Number: 20130133112
Publication Date: 2013-05-23
Inventor: HONDA MOTOR CO., LTD.,

Plant genome design method defines DNA markers M1 to M5, for target region, DNA marker M2 is defined at an end on an upstream side of a target region, or upstream thereof, DNA marker M1 is defined upstream of the DNA marker M2, DNA marker M4 is defined at an end on a downstream side of the target region, or downstream thereof, DNA marker M5 is defined downstream of the DNA marker M4, and DNA marker M3 is defined in the target ...

COMPOSITIONS AND METHODS OF USE OF MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE

Application Number: 20130133111
Publication Date: 2013-05-23
Inventor: Pioneer Hi-Bred International, Inc.,

Methods and compositions for modulating plant response, development and yield under varying environmental conditions are provided. Methods employing MAPKKK are provided. The MAPKKK sequences are used in a variety of methods including modulating root development, modulating leaf and/or shoot development, modulating tolerance under abiotic stress and modulating yield. Transformed plants, plant cell, tissues, seed and expression vectors are also ...

TRANSCRIPTIONAL ACTIVATORS INVOLVED IN ABIOTIC STRESS TOLERANCE

Application Number: 20130133110
Publication Date: 2013-05-23
Inventor: Pioneer Hi-Bred International Inc.,

The present invention provides compositions and methods for regulating expression of nucleotide sequences in a plant. Compositions comprise novel polypeptides involved in modulating gene expression in response to abiotic stress such as cold or drought, and the polynucleotides encoding the polypeptides. Methods for expressing the polynucleotides in a plant and improving cold and/or drought tolerance of plants are also ...

CLOSTEROVIRUS VECTORS AND METHODS

Application Number: 20130133109
Publication Date: 2013-05-23
Inventor: Education on behalf of Oregon State University, State of Oregon Acting by and through the State Board of Higher

The present disclosure relates to the development and use of Closterovirus-based vectors for the delivery of nucleotides to plants. Specifically, the present disclosure provides viral vectors based on Grapevine leafroll-associated virus-2 for the delivery and expression of genes in plants, particularly grape plants. Methods of making and using these vectors, as well as the plants transformed by these vectors, are also ...

EXTRACTS FROM PIRIN+ AND PIRIN- PLANTS AND USES THEREOF

Application Number: 20130133108
Publication Date: 2013-05-23
Inventors: Warpeha, Katherine; Kaufman, Lon

The present disclosure provides methods of making and using plant extracts that include quercetin, which are generated from transgenic plants that have decreased pirin activity (prn-). Such transgenic plants and their extracts can be used to increase tolerance of a plant to a stressor, such as UV light, as well as treat tumor cells (such as kill cancer cells), prevent certain types of fungal infections (such as C. gattii), and increase antioxidant activity. The present disclosure also ...

GENES ENCODING NEMATODE TOXINS

Application Number: 20130133107
Publication Date: 2013-05-23
Inventor: Athenix Corporation,

Compositions and methods for conferring nematicidal activity to bacteria, plants, plant cells, tissues and seeds are provided. Compositions including a coding sequence for nematicidal polypeptides are provided. The coding sequences can be used in DNA constructs or expression cassettes for transformation and expression in plants and bacteria. Compositions also include transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated nematicidal nucleic acid molecules are ...

ISOLATED POLYNUCLEOTIDES AND METHODS AND PLANTS USING SAME FOR REGULATING PLANT ACIDITY

Application Number: 20130133106
Publication Date: 2013-05-23
Inventors: Cohen, Shahar; Katzir, Nurit; Schaffer, Arthur A.; Burger, Yosef

Provided are isolated polynucleotides comprising a nucleic acid sequence encoding a polypeptide, wherein the polypeptide modulates acidity of a plant. Also provided are nucleic acid constructs and plant cells comprising same and methods of using same for modulating acidity of a ...

PLANT CYTOCHROME P450

Application Number: 20130133105
Publication Date: 2013-05-23
Inventors: Graham, Ian Alexander; Winzer, Thilo; Walker, Tracy Carol

This disclosure relates to the isolation and sequencing of nucleic acid molecules that encode cytochrome P450 polypeptides from a Papaver somniferum cultivar; uses in the production of noscapine and identification of poppy cultivars that include genes that comprise said nucleic acid ...

PLANTS HAVING ALTERED AGRONOMIC CHARACTERISTICS UNDER NITROGEN LIMITING CONDITIONS AND RELATED CONSTRUCTS AND METHODS INVOLVING GENES ENCODING LNT5 POLYPEPTIDES AND HOMOLOGS THEREOF

Application Number: 20130133104
Publication Date: 2013-05-23
Inventors: E I Du Pont De Nemours And Company, ; Pioneer Hi Bred International Inc,

Isolated polynucleotides and polypeptides and recombinant DNA constructs particularly useful for altering agronomic characteristics of plants under nitrogen limiting conditions compositions (such as plants or seeds) comprising these recombinant DNA constructs, and methods utilizing these recombinant DNA constructs. The recombinant DNA construct comprises a polynucleotide operably linked to a promoter functional in a plant, wherein said polynucleotide encodes a LNT5 ...

MANIPULATION OF GLUTAMINE SYNTHETASES (GS) TO IMPROVE NITROGEN USE EFFICIENCY AND GRAIN YIELD IN HIGHER PLANTS

Application Number: 20130133103
Publication Date: 2013-05-23
Inventor: Pioneer Hi-Bred International, Inc.,

The present invention provides polynucleotides and related polypeptides of the protein GS. The invention provides genomic sequence for the GS gene. GS is responsible for controlling nitrogen utilization efficiency in plants. Glutamine synthase sequences are provided for improving grain yield and plant growth. The invention further provides recombinant expression cassettes, host cells and transgenic ...

TARGETING SIGNAL FOR INTEGRATING PROTEINS, PEPTIDES AND BIOLOGICAL MOLECULES INTO BACTERIAL MICROCOMPARTMENTS

Application Number: 20130133102
Publication Date: 2013-05-23
Inventors: Kerfeld, Cheryl A.; Kinney, James N.

A conserved region of sequence in bacterial microcompartment (BMC) enzymes and proteins was identified. Peptide sequences derived from this conserved region of native BMC proteins and enzymes appear to target the hexameric facets of BMC shell proteins. These peptides were predicted to share general properties of a predicted alpha helical conformation, flanked by poorly conserved segment(s) of primary structure); for each type of encapsulated protein, and for each functionally distinct BMC. ...

PLANTS RESISTANT TO PATHOGENS AND METHODS FOR PRODUCTION THEREOF

Application Number: 20130133101
Publication Date: 2013-05-23
Inventors: Rodiuc, Natalia; Marco, Yves; Keller, Harald; Favery, Bruno

The present invention relates to plant genes involved in negative regulation of resistance to plant pathogens and uses thereof. More particularly, the invention relates to plants having a defective phytosulfokine (PSK) function and exhibiting an increased resistance to plant pathogens. The invention also relates to methods for producing modified plants resistant to various diseases. Furthermore, the invention relates to plants having a defective PSK receptor (PSKR) function, and to methods of ...

RADISH CULTIVAR E66V70336

Application Number: 20130133100
Publication Date: 2013-05-23
Inventor: SCHIEDER, ANDREA

A radish line designated E66V70336 is disclosed. The invention relates to the seeds of radish cultivar E66V70336, to the plants and plant parts of radish cultivar E66V70336 and to methods for producing a radish plant, either inbred or hybrid, by crossing the radish cultivar E66V70336 with itself or another radish line. The invention further relates to methods for producing a radish plant containing in its genetic material one or more transgenes and to the transgenic plants produced by that ...

CANOLA CULTIVAR G152964H

Application Number: 20130133099
Publication Date: 2013-05-23
Inventors: Gingera, Gregory R.; Knievel, Donna C.; Kubik, Thomas J.

The present invention relates to a new and distinctive canola, designated G152964H. Also included are seeds of canola G152964H, to the plants, or plant parts, of canola G152964H and to methods for producing a canola plant produced by crossing the canola G152964H with itself or another canola genotype, and the creation of variants by mutagenesis or transformation of canola ...

CANOLA CULTIVAR G152950H

Application Number: 20130133098
Publication Date: 2013-05-23
Inventors: Gingera, Gregory R.; Knievel, Donna C.; Kubik, Thomas J.

The present invention relates to a new and distinctive canola, designated G152950H. Also included are seeds of canola G152950H, to the plants, or plant parts, of canola G152950H and to methods for producing a canola plant produced by crossing the canola G152950H with itself or another canola genotype, and the creation of variants by mutagenesis or transformation of canola ...

CANOLA CULTIVAR G069467

Application Number: 20130133097
Publication Date: 2013-05-23
Inventors: Gingera, Gregory R.; Kubik, Thomas J.

The present invention relates to a new and distinctive canola, designated G069467. Also included are seeds of canola G069467, to the plants, or plant parts, of canola G069467 and to methods for producing a canola plant produced by crossing the canola G069467 with itself or another canola genotype, and the creation of variants by mutagenesis or transformation of canola ...

CANOLA CULTIVAR CL121460H

Application Number: 20130133096
Publication Date: 2013-05-23
Inventors: Beaith, Michelle E.; Ripley, Van L.

The present invention relates to a new and distinctive canola, designated CL121460H. Also included are seeds of canola CL121460H, to the plants, or plant parts, of canola CL121460H and to methods for producing a canola plant produced by crossing the canola CL121460H with itself or another canola genotype, and the creation of variants by mutagenesis or transformation of canola ...

CANOLA CULTIVAR CL117235H

Application Number: 20130133095
Publication Date: 2013-05-23
Inventors: Beaith, Michelle E.; Ripley, Van L.

The present invention relates to a new and distinctive canola, designated CL117235H. Also included are seeds of canola CL117235H, to the plants, or plant parts, of canola CL117235H and to methods for producing a canola plant produced by crossing the canola CL117235H with itself or another canola genotype, and the creation of variants by mutagenesis or transformation of canola ...

CANOLA CULTIVAR DN051465

Application Number: 20130133094
Publication Date: 2013-05-23
Inventors: Kubik, Thomas J.; Chungu, Chibwe

The present invention relates to a new and distinctive canola, designated DN051465. Also included are seeds of canola DN051465, to the plants, or plant parts, of canola DN051465 and to methods for producing a canola plant produced by crossing the canola DN051465 with itself or another canola genotype, and the creation of variants by mutagenesis or transformation of canola ...

RECOMBINANT CONSTRUCTS AND TRANSGENIC FLUORESCENT ORNAMENTAL FISH THEREFROM

Application Number: 20130133093
Publication Date: 2013-05-23
Inventor: YORKTOWN TECHNOLOGIES, L.P.,

The present invention relates to the method and use of reef coral fluorescent proteins in making transgenic red, green and yellow fluorescent zebrafish. Preferably, such fluorescent zebrafish are fertile and used to establish a population of transgenic zebrafish and to provide to the ornamental fish industry for the purpose of marketing. Thus, new varieties of ornamental fish of different fluorescence colors from a novel source are ...

SEQUENCE-SPECIFIC DNA RECOMBINATION IN EUKARYOTIC CELLS

Application Number: 20130133092
Publication Date: 2013-05-23
Inventor: Droge, Dr. Peter

The present invention relates to a method of sequence specific recombination of DNA in eukaryotic cells utilizing att sequences from the bacteriophage lambda. A particular embodiment of the invention relates to a method further comprising performing the sequence specific recombination of DNA with an Int and a Xis factor. The present invention further relates to vectors containing each of these sequences and their use as ...

Human Monoclonal Antibodies To Programmed Death 1 (PD-1) And Methods For Treating Cancer Using Anti-PD-1 Antibodies Alone Or In Combination With Other Immunotherapeutics

Application Number: 20130133091
Publication Date: 2013-05-23
Inventors: Wang, Changyu; Sellby, Mark J.; Chen, Bing; Huang, Haichun; Srinivasan, Mohan; Korman, Alan J.; Cardarelli, Josephine M.

The present invention provides isolated monoclonal antibodies, particularly human monoclonal antibodies, that specifically bind to PD-1 with high affinity. Nucleic acid molecules encoding the antibodies of the invention, expression vectors, host cells and methods for expressing the antibodies of the invention are also provided. Immunoconjugates, bispecific molecules and pharmaceutical compositions comprising the antibodies of the invention are also provided. The invention also provides methods ...

TRANSGENIC MAMMALLS MODIFIED IN BRI PROTEIN EXPRESSION

Application Number: 20130133090
Publication Date: 2013-05-23
Inventors: D'Adamio, Luciano; Giliberto, Luca

Provided are non-human mammals comprising a knock-in nucleic acid sequence capable of causing an alteration of expression of wild-type Bri2 in the mammal or a knockout of wild-type Bri2. Also provided are the non-human mammals as a model for Alzheimer's ...

HIGH AFFINITY LEPTINS AND LEPTIN ANTAGONISTS

Application Number: 20130133089
Publication Date: 2013-05-23
Inventors: Gertler, Arieh; Elinav, Eran; Halpern, Zamir

Leptin muteins, in particular leptin antagonists, with increased binding affinity to leptin receptor are provided. These compounds as well as pharmaceutical composition comprising them are useful for the treatment of any disorder in which a non-desirable or deleterious activity of endogenous leptin or an altered innate immune response is ...

EXPRESSION OF SECRETED HUMAN ALPHA-FETOPROTEIN IN TRANSGENIC ANIMALS

Application Number: 20130131317
Publication Date: 2013-05-23
Inventor: Merrimack Pharmaceuticals, Inc.,

The invention features a process of expressing secreted recombinant human alpha-fetoprotein (rHuAFP) in the milk or urine of transgenic ...

GDE Compositions and Methods

Application Number: 20130131144
Publication Date: 2013-05-23
Inventor: The Johns Hopkins University,

The present invention relates to compositions to treat glycerophosphodiester phosphodiesterase (GDE) related disorders. The invention also relates to methods treating GDE related disorders. The invention further relates to kits for treating GDE related disorders in a subject. The invention further relates to methods of identifying novel treatments for treating GDE related disorders in a ...

AMINO ACID SEQUENCES DIRECTED AGAINST GPCRS AND POLYPEPTIDES COMPRISING THE SAME FOR THE TREATMENT OF GPCR-RELATED DISEASES AND DISORDERS

Application Number: 20130130379
Publication Date: 2013-05-23
Inventor: Ablynx N.V.,

The present invention relates to amino acid sequences that are directed against G-protein coupled receptors (GPCRs), as well as to compounds or constructs, and in particular proteins and polypeptides, that comprise or essentially consist of one or more such amino acid sequences. The invention also relates to nucleic acids encoding such amino acid sequences and; to methods for preparing such amino acid sequences and polypeptides; to host cells expressing or capable of expressing such amino acid ...

Polypeptides Having Beta-Glucosidase Activity, Beta-Xylosidase Activity, or Beta-Glucosidase and Beta-Xylosidase Activity and Polynucleotides Encoding Same

Application Number: 20130130327
Publication Date: 2013-05-23
Inventors: Novozymes, Inc., ; Novozymes A/S,

The present invention relates to isolated polypeptides having beta-glucosidase activity, beta-xylosidase activity, or beta-glucosidase and beta-xylosidase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the ...

Polypeptides Having Beta-Glucosidase Activity, Beta-Xylosidase Activity, or Beta-Glucosidase and Beta-Xylosidase Activity and Polynucleotides Encoding Same

Application Number: 20130130326
Publication Date: 2013-05-23
Inventors: Novozymes, Inc., ; Novozymes A/S,

Polypeptides Having Beta-Glucosidase Activity, Beta-Xylosidase Activity, or Beta-Glucosidase and Beta-Xylosidase Activity and Polynucleotides Encoding Same

Application Number: 20130130325
Publication Date: 2013-05-23
Inventors: Novozymes, Inc., ; Novozymes A/S,

Expression of Proteins in Plants

Application Number: 20130130314
Publication Date: 2013-05-23
Inventor: University of Cape Town,

The invention relates to a method of producing an influenza virus H5 polypeptide in a plant comprising the steps of cloning an influenza H5 gene or nucleic acid encoding its functional equivalent into a vector adapted to target components present in the plant, infiltrating at least a portion of the plant with the vector or transforming plant tissue with the vector so as to transiently express the influenza virus H5 polypeptide, and/or to create a transgenic plant; and recover the influenza ...

PLANT HAEMOGLOBIN

Application Number: 20130125268
Publication Date: 2013-05-16
Inventors: Mulet Salort, Jose Miguel; Serrano Salom, Ramon; Sanz Molinero, Ana Isabel

The invention relates generally to a method for improving growth of plants, under normal and under stress conditions, more particularly under osmotic stress and/or temperature extremes, comprising modifying plant haemoglobin gene expression and/or by modifying plant haemoglobin protein levels in a plant. The invention furthermore relates to a method for increasing yield of a plant, comprising modifying plant gene expression and/or by modifying plant haemoglobin levels in a plant. The invention ...

Pesticidal Mixtures

Application Number: 20130125267
Publication Date: 2013-05-16
Inventors: Sikuljak, Tatjana; Gewehr, Markus; Langewald, Juergen; Pohlman, Matthias

The present invention, comprising: [(3S,4R,4aR,6S,6aS,12R,12a5,12b5)-3-(cyclopropanecarbonyloxy)-6,12-dihy-droxy-4,6a,12b-trimethyl-11-oxo-9-(pyridin-3-yl)-1,2,3,4,4a,5,6,6a,12a,12b-decahydro-11H,12H-benzo[f]pyrano[4,3-b]chromen-4-yl]methyl cydopropanecarboxylate (compound II) and a pesticidal compound II; in synergistic effective amounts.

METHOD FOR GENE INTRODUCTION INTO HORDEUM PLANT USING AGROBACTERIUM, AND METHOD FOR PRODUCTION OF TRANSFORMED PLANT OF HORDEUM PLANT

Application Number: 20130125266
Publication Date: 2013-05-16
Inventors: Ishida, Yuji; Hiei, Yukoh

An object of the present invention is to provide a method of gene introduction, which can transform a Hordeum plant at a higher efficiency compared to that in known Agrobacterium methods, and a method of producing a transformed Hordeum plant. The method of the invention includes a step of subjecting an immature embryo tissue of a Hordeum plant to centrifugation treatment and/or pressurization treatment before the inoculation with Agrobacterium, during the ...

AGROBACTERIUM-MEDIATED METHOD FOR PRODUCING TRANSFORMED PLANT

Application Number: 20130125265
Publication Date: 2013-05-16
Inventor: JAPAN TOBACCO INC.,

The present invention aims to provide a novel Agrobacterium-mediated method for producing a transformed plant.

The method of the present invention is an Agrobacterium-mediated method for producing a transformed plant, which comprises:

- (i) a coculture step for culturing an Agrobacterium-inoculated ...

Plants Having Enhanced Yield-Related Traits and a Method for Making the Same

Application Number: 20130125264
Publication Date: 2013-05-16
Inventors: Vandenabeele, Steven; Frankard, Valerie

Nucleic acids and the encoded embryonic flower 2 (EMF2) polypeptides or Ubiquitin C-terminal Hydrolase 1 (UCH1-like) polypeptides are provided. A method of enhancing yield-related traits in plants by modulating expression of nucleic acids encoding EMF2 polypeptides or UCH1-like polypeptides is provided. Plants with modulated expression of the nucleic acids encoding EMF2 polypeptides or UCH1-like polypeptides have enhanced yield-related traits relative to control ...

TRANSGENIC PLANTS HAVING INCREASED BIOMASS

Application Number: 20130125263
Publication Date: 2013-05-16
Inventors: Sharma, Vijay; Wu, Chuan-Yin; Apuya, Nestor

Methods and materials for modulating biomass levels in plants are disclosed. For example, nucleic acids encoding biomass-modulating polypeptides are disclosed as well as methods for using such nucleic acids to transform plant cells. Also disclosed are plants having increased biomass levels and plant products produced from plants having increased biomass ...

PLANTS HAVING ENHANCED YIELD-RELATED TRAITS AND A METHOD FOR MAKING THE SAME

Application Number: 20130125262
Publication Date: 2013-05-16
Inventors: Russinova, Jenny; Reuzeau, Christophe

The present invention relates generally to the field of molecular biology and concerns a method for enhancing various economically important yield-related traits in plants. More specifically, the present invention concerns a method for enhancing yield-related traits in plants by modulating expression in a plant of a nucleic acid encoding an POI (Protein Of Interest) polypeptide. The present invention also concerns plants having modulated expression of a nucleic acid encoding an POI polypeptide, ...

DNA SEQUENCE CONTAINING THE PROMOTER REGION AND REGULATORELEMENTS OF THE MEC1 GENE, EXPRESSED IN CASSAVA ROOTS, FOR USE IN GENETIC IMPROVEMENT PROGRAMS

Application Number: 20130125261
Publication Date: 2013-05-16
Inventors: Batista De Souza, Cláudia Regina; Lima Aragão, Francisco José; De Oliveira Moreira, Edith Cibelle; Bezerra Nascimento, Soelange; Castelo Blanco Carvalho, Luiz Joaquim

The present invention refers to a promoter and/or specific regulatory regions for the expression of genes of interest in roots. The invention further describes DNA constructs containing the polynucleotide of the invention operatively linked to a heterologous and/endogenous gene. Besides, the invention refers to the use of these constructions in the form of expression vectors, recombinant vectors and in plants, plant cells or transgenic protoplasts. The invention further describes a method ...

BIOASSAY FOR GENE SILENCING CONSTRUCTS

Application Number: 20130125260
Publication Date: 2013-05-16
Inventor: VENGANZA INC.,

The invention provides constructs and methods of screening for constructs useful in conferring resistance in plants to pests by gene silencing. The invention also provides pest-resistant plants transformed with the present constructs. One screening method of the invention comprises the steps of: selecting at least one pest target nucleotide sequence, producing a plurality of dsRNA test agents that target the pest target nucleotide sequence, testing and scoring the plurality of dsRNA test agents ...

RNA INTERFERENCE MEDIATING SMALL RNA MOLECULES

Application Number: 20130125259
Publication Date: 2013-05-16
Inventors: Wissenschaften E.V., Max-Planck-Gesellschaft zur Forderung der; Whitehead Institute For Biomedical Research, ; University Of Massachusetts, ; Massachusetts Institute Of Technology,

Double-stranded RNA (dsRNA) induces sequence-specific post-transcriptional gene silencing in many organisms by a process known as RNA interference (RNAi). Using a Drosophila in vitro system, we demonstrate that 19-23 nt short RNA fragments are the sequence-specific mediators of RNAi. The short interfering RNAs (siRNAs) are generated by an RNase III-like processing reaction from long dsRNA. Chemically synthesized siRNA duplexes with overhanging 3′ ends mediate efficient target RNA ...

ISOLATED POLYNUCLEOTIDES AND POLYPEPTIDES FOR INCREASING PLANT YIELD AND/OR AGRICULTURAL CHARACTERISTICS

Application Number: 20130125258
Publication Date: 2013-05-16
Inventors: Emmanuel, Eyal; Karchi, Hagai

Provided are isolated polynucleotides which comprise a nucleic acid sequence at least 80% identical to SEQ ID NO: 321, 1-320, 322-480, 793-2945 or 2946; isolated polypeptides which comprise an amino acid sequence at least 80% homologous to SEQ ID NO: 517, 481-516, 518-792, 2947-4662 or 4663, nucleic acid constructs comprising same, transgenic cells and plants expressing same and methods of using same for increasing yield, biomass, growth rate, vigor, oil content, fiber yield, fiber quality, ...

CORN WITH INCREASED YIELD AND NITROGEN UTILIZATION EFFICIENCY

Application Number: 20130125257
Publication Date: 2013-05-16
Inventor: Church, Jeffrey

The subject invention relates in part to the use of insect-protected corn to modify fertility recommendations for given yield targets on any transgenic corn ...

NITRATE TRANSPORT COMPONENTS

Application Number: 20130125256
Publication Date: 2013-05-16
Inventors: Pioneer Hi Bred International Inc, ; E I Du Pont De Nemours And Company,

This invention relates to isolated nucleic acid fragments encoding high affinity nitrate transport components. The invention also relates to the construction of recombinant DNA constructs encoding all or a portion of nitrate transport components, in sense or antisense orientation, wherein expression of the recombinant DNA construct may alter levels of the nitrate transport components in a transformed host ...

Transgenic Plants With Increased Stress Tolerance and Yield

Application Number: 20130125255
Publication Date: 2013-05-16
Inventor: BASF Plant Science GmbH,

Polynucleotides are disclosed which are capable of enhancing a growth, yield under water-limited conditions, and/or increased tolerance to an environmental stress of a plant transformed to contain such polynucleotides. Also provided are methods of using such polynucleotides and transgenic plants and agricultural products, including seeds, containing such polynucleotides as ...

CITRUS TRISTEZA VIRUS BASED VECTORS FOR FOREIGN GENE/S EXPRESSION

Application Number: 20130125254
Publication Date: 2013-05-16
Inventor: University of Florida Research Foundation, Inc.,

Disclosed herein are viral vectors based on modifications of the Citrus Tristeza virus useful for transfecting citrus trees for beneficial purposes. Included in the disclosure are viral vectors including one or more gene cassettes that encode heterologous polypeptides. The gene cassettes are positioned at desirable locations on the viral genome so as to enable expression while preserving functionality of the virus. Also disclosed are methods of transfecting plants and plants transfected with ...

INSECT RESISTANT COTTON PLANTS AND METHODS FOR IDENTIFYING SAME

Application Number: 20130125253
Publication Date: 2013-05-16
Inventors: TROLINDER, Linda; Habex, Veerle; Moens, Sofie; Paelinck, Dimitri; Berghman, Evelien

The invention provides specific transgenic cotton plants, plant material and seeds, characterized in that these products harbor a specific transformation event at a specific location in the cotton genome. Tools are also provided which allow rapid and unequivocal identification of the event in biological ...

NOVEL ANTI-IGF-IR ANTIBODIES AND USES THEREOF

Application Number: 20130125252
Publication Date: 2013-05-16
Inventor: PIERRE FABRE MEDICAMENT,

The present invention relates to novel antibodies capable of binding specifically to the human insulin-like growth factor I receptor (IGF-IR). The invention likewise comprises the use of these antibodies as a medicament for the prophylactic and/or therapeutic treatment of cancers overexpressing IGF-IR, stimulated either by IGF1 and/or IGF2, or any pathology connected with the overexpression of said receptor as well as in processes or kits for diagnosis of illnesses connected with the ...

HUMAN MONOCLONAL ANTIBODIES TO PROGRAMMED DEATH LIGAND 1 (PD-L1)

Application Number: 20130122014
Publication Date: 2013-05-16
Inventor: Medarex, Inc.,

The present disclosure provides isolated monoclonal antibodies, particularly human monoclonal antibodies that specifically bind to PD-L1 with high affinity. Nucleic acid molecules encoding the antibodies of this disclosure, expression vectors, host cells and methods for expressing the antibodies of this disclosure are also provided. Immunoconjugates, bispecific molecules and pharmaceutical compositions comprising the antibodies of the invention are also provided. The disclosure also provides ...