There is always a new coming into the market and I don’t know if that is a good thing or a bad thing. Has anybody heard or experience any negative results from taking metformin???

(well thats the way I read it)

The reason isn’t because these people speculate on getting their frozen head reattached to a new body, but they actually hope that the information patterns in their brains stay intact enough to be reconstructed and emulated on a computer/robot. If you have a reductionist worldview (which is the one and only scientifically sound worldview as of now) then there is no problem with this approach and we could reconstruct and upload a brain into a computer, and that upload would then be you – you’d be dead and wake up in new body and not even notice the difference at first, because all your memories and your personality would be intact, if the information has remained intact enough. You would have switched the medium but it would still be you and you would still feel like yourself.

There is nothing known in the laws of physics that would prohibit this from working – but that said, I haven’t seen conclusive evidence that our current preservation technology (liquid nitrogen) really preserves the brain well enough for a reconstruction. The question is also “how well is well enough” – do you have to reconstruct a brain down to the molecular level, or does the cellular level suffice? Still, I’d take my chances if there actually was a company that offered me the option of cryonics in my country.

In conclusion, you’ve missed the main point of cryonics: Most (or at least most reasonable) cryonicists don’t really expect to be reawakened in their old body, many just want their brains uploaded into a new body and afterwards continue their new life in the future. There’s nothing unreasonable about taking that gamble with the grim reaper – even if your chances of survival and reconstruction were as low as 5%, this still beats the 100% chance that you’re dead if you just let your corpse rot or burn instead.

I would add that in most of the world rest is considered healthful and exercise is anathema.

I doubt there has been a study that can control for that because you would have to take a random population of non or mild exercisers and have a group exercise more for their entire lives to measure lifespan. Difficult and expensive. On the extreme end it seems obesity amd shortened lifespan is clearly linked.

I have been going to the gym simce a teenager and I certainly subscribe to the endorphin effects.